Abstract: Objective To investigate the therapeutic effect of Xuansu Zhike Decoction combined with glucocorticoid on bronchopneumonia and its influence on procalcitonin (PCT) and hypersensitive C-reactive protein (hsCRP). Methods 100 children with bronchopneumonia admitted to Dunhuang City Hospital from January 2020 to November 2022 were selected as study subjects and divided into observation group and control group by random lottery, with 50 cases in each group. The children in the control group were treated with conventional symptomatic treatment, while the children in the observation group were treated with Xuansu Zhike Decoction combined with glucocorticoids on the basis of conventional symptomatic treatment, and their clinical efficacy, symptom disappearance time and hospitalization time were compared, as well as the expression level of inflammatory factors before and after treatment in the two groups. Results The total response rate in the observation group was significantly higher than the control group (P<0.05); the disappearance time of lung rale/wheezing, cough, total days of fever and hospital stay in the observation group were significantly lower than those in the control group (P<0.05); there was no significant difference in the expression levels of WBC, PCT and hsCRP between the two groups before treatment (P>0.05). After treatment, the expression levels of WBC, PCT and hsCRP in the two groups decreased, and the observation group was lower than the control group (P<0.05). Conclusion Xuansu Zhike Decoction combined with glucocorticoid is effective in the treatment of bronchopneumonia, which can reduce the duration of symptoms, reduce the level of inflammatory factors such as PCT and hsCRP, and promote the early recovery of children.

Key words: Xuansu Zhike decoction, glucocorticoid, bronchial pneumonia, procalcitonin, high sensitivity C-reactive protein