Abstract: The occurrence and development of myocardial ischemia-reperfusion injury (MIRI) is closely related to the relationship between qi, blood and body fluid. Physiologically, qi, blood, and body fluid are the basic substances for energy metabolism of myocardial cells, and pathologically, these substances are basic factors that damage the function of myocardial cells. With the in-depth study of autophagy, it was found that the metabolic role of autophagy in ischemia-reperfusion injury myocardial cells is similar to the function of qi, blood and body fluids. The imbalance of autophagy will lead to qi deficiency and stagnation, and the lack of autophagy will lead to the accumulation of blood stasis and phlegm. Therefore, this paper constructs the research idea of "autophagy-qi, blood and body fluid-myocardial ischemia-reperfusion injury", so as to promote greater innovation and breakthrough in the prevention and treatment of MIRI by traditional Chinese medicine.

Key words: autophagy, qi, blood and body fluid, myocardial ischemia-reperfusion injury, research ideas