Analysis of Risk Factors of Infection and Clinical Significance of Serum PCT, TNF-α and WBC after Percutaneous Nephrolithotomy in Patients with Upper Urinary Tract Calculi

Abstract

Abstract: Objective To explore the risk factors of postoperative urinary tract infection in patients with upper urinary tract calculi and the diagnostic value of serum PCT, TNF - α and WBC for postoperative urinary tract infection. Methods The data of 118 patients with upper urinary tract calculi who underwent percutaneous nephrolithotomy in the Department of Urology, Beijing Nuclear Industry Hospital from June 2014 to June 2021 were retrospectively analyzed. Logistic regression was used to analyze the risk factors of postoperative urinary tract infection in patients; serum PCT and TNF-α expression levels in patients with or without infection were detected by ELISA, and WBC counts in peripheral blood were recorded. Diagnostic value of postoperative urinary tract infection. Results Stone size, operation time, positive urine culture and positive urine protein were the risk factors of postoperative urinary tract infection (P<0.05). AUC for PCT, TNF- α, WBC, and combined analysis curve were 0.903, 0.893, 0.854 and 0.994, respectively. Conclusions tone size, operation time and preoperative urinary tract infection are the risk factors of postoperative urinary tract infection. The combined analysis of postoperative PCT, TNF - α and WBC get the best diagnostic efficacy for urinary tract infection.

Key words: upper urinary tract calculi, urinary tract infection, percutaneous nephrolithotomy

CLC Number:

PANG Hua, BIAN Jian-hua, LIU Wen-jie, ZHI Jing-tao. Analysis of Risk Factors of Infection and Clinical Significance of Serum PCT, TNF-α and WBC after Percutaneous Nephrolithotomy in Patients with Upper Urinary Tract Calculi[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(4): 15-18.

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