Effect of Circulatory Ischemic Vertigo on Blood Supply and Hemorheology Indexes of Vertebrobasilar Artery after Treatment with Ginkgo Damo Injection and Betahistine Mesylate Tablets for Injection

Abstract

Abstract: Objective To explore the effect of Ginkgo Damo Injection combined with Betahistine Mesylate Tablets on vertebrobasilar artery blood supply and blood flow indexes after the treatment of circulating ischemic vertigo. Methods 80 patients with posterior circulation ischemic vertigo who were admitted to Dongchangfu People's Hospital from September 2018 to September 2020 were randomly selected for research, and divided into control group and experimental group by random number table method, with 40 cases in each group. The control group was treated with Betahistine Mesylate Tablets, the experimental group was treated with Ginkgo Damo Injection combined with Betahistine Mesylate Tablets, the therapeutic effect was compared, and the blood flow velocity, hemorheology index, adverse reactions on both sides of the vertebral body and vertebral base rate and degree of vertigo disability were compared. Results The total effective rate of experimental group was higher than that of control group(P<0.05); after treatment, the blood flow velocity of left vertebral artery, right vertebral artery and basilar artery in the two groups were higher than before (P<0.05), and the experimental group was higher than the control group (P<0.05). After treatment, the whole blood high shear viscosity, whole blood low shear viscosity, plasma viscosity and fibrinogen in two groups were lower than before (P<0.05), and the experimental group was lower than the control group (P<0.05). The total incidence of adverse reactions such as rash, nausea and vomiting, headache and head distension in experimental group had no difference with that in control group (P>0.05). After treatment, somatic, emotionality and functional scores of DHI scale in 2 groups were lower than before (P<0.05), and inter-group comparison of experimental group was lower than control group (P<0.05). Conclusion In the treatment of patients with posterior circulation ischemic vertigo, Ginkgo Damole Injection combined with Betahistine Mesylate Tablets has outstanding therapeutic effect and few adverse reactions, and can effectively improve the vertebrobasilar artery blood flow velocity, hemorheology and vertigo disability degree, it is worth learning.

Key words: posterior circulation, ischemia, dizziness, Betahistine Mesylate Tablets, Ginkgo Damo Injection

CLC Number:

R741

WANG Hai-tao, KONG Yan-ni. Effect of Circulatory Ischemic Vertigo on Blood Supply and Hemorheology Indexes of Vertebrobasilar Artery after Treatment with Ginkgo Damo Injection and Betahistine Mesylate Tablets for Injection[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(3): 48-51.

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