Abstract: Objective To investigate the quality of life of postmenopausal osteoporosis patients in Zhongshan City, and to analysis the related influencing factors. Methods A total of 200 cases of postmenopausal osteoporosis patients in Zhongshan area who were in the orthopaedic outpatient department and hospitalized in our hospital from January 2022 to June 2022 were selected as the study group (BMD<M-2SD). During the same period, the other 200 cases of healthy postmenopausal patients without osteoporosis who underwent physical examination in our hospital were selectedas the control group (BMD>M-1SD). The Chinese version of the WHOQOL-BREF questionnaire were used to evaluate the quality of life of all the participants, and general data were investigated and multivariate analysis were performed. Results The quality of life scores of the study group were significantly lower than those of the control group (P<0.05). There were no significant differences in marital status, occupation, etc. Compared between the study group and the control group (P>0.05), but there were significant differences in age, menopause years, smoking, and years of education compared between the study group and the control group (P<0.05). In the study group, Spearsman analysis showed that age, years of menopause, smoking, years of education were correlated with the total score of quality of life (P<0.05). Logistic regression showed that age, years of menopause, smoking and years of education were risk factors affected the quality of life of patients (P<0.05). Conclusion The quality of life of postmenopausal osteoporosis patients in Zhongshan is relatively low, and age, menopause years, smoking, and years of education are the risk factors for the low quality of life of postmenopausal osteoporosis patients in ZhongshanCity.

Key words: postmenopausal osteoporosis, quality of life, impact factors, years of menopause