ZHONGHUA YANGSHENG BAOJIAN ›› 2022, Vol. 40 ›› Issue (20): 58-60.

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Progress in Noncoding RNA Regulation Oral Squamous Cell Carcinoma Proliferation

JIANG Yu-feng1, XU Xin-li1, CAO Xiao-hua2,*   

  1. 1. Department of Medical Laboratory, Jining No. 1 People's Hospital, Jining Shandong, 272100, China;
    2. Intensive Care Unit,Jining No. 1 People's Hospital, Jining Shandong, 272100, China
  • Online:2022-10-16 Published:2022-10-14

Abstract: Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in oral and maxillofacial region. It often metastases to local lymph nodes, and distant metastasis may occur in late stage, which seriously affects the survival and quality of life of patients. Noncoding RNAs are widely found in eukaryotes, RNAs that cannot encode proteins, including miRNAs, LncRNAs, circRNAs, etc. The regulatory relationship between non-coding RNAs in the proliferation of OSCC has become a research hotspot, and it has been proved that non-coding RNAs play an important regulatory role in the occurrence and development of OSCC. At present, the specific regulatory mechanism of non-coding RNAs in the occurrence and development of OSCC has not been fully clarified, and it has become a scientific problem that needs to be solved urgently in basic and clinical practice. Therefore, we review the mechanisms of noncoding RNA regulation OSCC proliferation to provide theory foundation for OSCC diagnosis and treatment.

Key words: non-coding RNA, OSCC, proliferation

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