Abstract: Objective To explore and analysis the diagnostic values of ultrasonic elastography combined with hysteroscopy for uterine cavity lesions. Methods From April 2020 to December 2022, 87 cases of patients with uterine cavity lesions who were diagnosed and treated at Zibo Maternal and Child Health Hospital were selected as the research subjects. All patients were underwent ultrasonic elastography combined with hysteroscopy, and pathological examination were performed to determine the diagnostic value. Results The pathological diagnosis were endometrial cancer in 17 cases (malignant group), endometrial polyps in 32 cases, endometritis in 18 cases, submucosal fibroids in 16 cases, and atypical endometrial hyperplasia in 4 cases (benign group) in the 87 cases. The ultrasound elastography score of the malignant group were significantly higher than that of the benign group (P<0.05), with 14 cases diagnosed as malignant and 73 cases as benign. Hysteroscopy diagnosed 13 cases of endometrial cancer, 33 cases of endometrial polyps, 19 cases of endometritis, 17 cases of submucosal fibroids, and 5 cases of atypical endometrial hyperplasia. The overall accuracy of hysteroscopy were 90.8%(79/87). The combination of ultrasonic elastography and hysteroscopy identified 16 cases of malignant lesions and 71 cases of benign lesions. The sensitivity of ultrasonic elastography, hysteroscopy, and the combination of ultrasonic elastography and hysteroscopy in differential diagnosis of benign and malignant uterine cavity lesions were 82.3% (14/17), 64.7% (11/17), and 94.1% (16/17), respectively, with specificity of 100.0% (70/70), 97.1% (68/70), and 100.0% (70/70). The sensitivity of ultrasonic elastography combined with hysteroscopy in differential diagnosis of benign and malignant uterine cavity lesions were higher than that of hysteroscopy (P<0.05). There were no significant difference in the diagnostic sensitivity and specificity of other methods (P>0.05). Conclusion Ultrasound elastography combined with hysteroscopy has higher sensitivity and specificity in the diagnosis of benign and malignant uterine cavity lesions, and has better application value.

Key words: elastic imaging technology, hysteroscopy, uterine cavity lesions, endometrial cancer, sensitivity, specificity