Abstract: Objective To explore the effect of IKAP mode on self-perceived burden and cancer related fatigue in Mammary cancer patients undergoing chemotherapy. Methods A total of 82 Mammary cancer patients admitted to Zaozhuang Municipal Hospital from January 2021 to December 2022 were selected as the research objects.According to the random number table, divided into observation group and control group,41 cases in each group.The control group was given routine intervention mode,the observation group was given IKAP mode.After intervention,the self-perceived burden,cancer-related fatigue and the improvement of quality of life were compared between the two groups. Results Before the intervention, the difference between self-perceived burden and cancer fatigue score between the two groups (P>0.05), the self-perceived burden and cancer fatigue score were lower than that of the control group, with a statistically significant difference (P<0.05).The five scores of patients were higher than those of the control group, which the difference was significant (P<0.05). Conclusion IKAP model can relieve negative emotion,reduce the burden of self-perceived and cancer related fatigue, and improve the quality of life of breast cancer patients.

Key words: information-knowledge-belief-behavior mode, mammary cancer, cancer related fatigue, self-perceived burden, quality of life