Abstract: ：Objective To explore the effect of reverse classroom teaching met hod of virtual patient combined with medical image archiving and communication system (picture archiving and communication system, PACS) in apprenticeship teaching of pulmonary embolism. Methods From September 2021 to September 2022, 64 clinical medical undergraduates of Grade 2017 and 2018 in Wenzhou Medical University, who were trainees in the Department of Respiratory Medicine of Yiwu Central Hospital, were randomly divided into control group (n=32) and experimental group (n=32). The control group was given general teaching method, and the experimental group was taught by virtual patient combined with PACS. Compare the basic theoretical knowledge, operation skills, medical record report and assessment score, teaching satisfaction, teaching evaluation score and so on between the two groups. Results The scores of basic theoretical knowledge, operation skills and medical record reporting in the experimental group were significantly higher than those in the control group (P<0.05). Teaching effect satisfaction rate and the scores of teaching evaluation in the experimental group were significantly higher than those in the control group (P<0.05). Conclusion Compared with the traditional teaching method, the flipped classroom teaching method of virtual patient combined with PACS has higher satisfaction,better teaching evaluation result and better examination result of basic theory in the experimental group, which is worthy of clinical application.

Key words: virtual patient, flipped classroom, PACS, interactive case teaching, clinical thinking