Influence of Stroke Volume Variation-guided Fluid Therapy on the Early Cognitive Function of Elderly Patients Following the Spinal Surgery

Abstract

Abstract: Objective To study the influence of stroke volume variation-guided fluid therapy on the early cognitive function of elderly patients following the spinal surgery. Methods A total of 80 elderly patients of undergoing the spinal surgery from February 2020 to February 2021 in Inner Mongolia Autonomous Region People's Hospital were chosen as research samples. According to random sampling method, patients were divided into study group 1 (stroke volume variation-guided fluid therapy) and study group 2 (central venous oxygen saturation-guided fluid therapy), 40 cases in each group. The intervention effects were probed. Results The global end-diastolic volume (GEDV), cardiac index(CI)and intrathoracic blood volume index (ITBVI) in study group 1 were higher than those of study group 2, but extravascular lung water index (EVLWI) and systemic vascular resistance index(SVRI) were lower than those of study group 2 (P<0.05); before treatment, mini-mental state examination(MMSE) scores between groups were not significantly different(P>0.05), after 6 h and 24 h of treatment, MMSE scores in study group 1 were higher than those of study group 2 (P<0.05). Conclusion The stroke volume variation-guided fluid therapy can stabilize the hemorheology, improve the early cognitive function. It is worthy of clinical application.

Key words: pinal surgery for the elderly, stroke volume variation, fluid therapy, cognitive function

CLC Number:

R614

HAO Wei, FAN Wei, WANG Jia-ni, WANG Chao. Influence of Stroke Volume Variation-guided Fluid Therapy on the Early Cognitive Function of Elderly Patients Following the Spinal Surgery[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(13): 1-4.

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