Abstract: Objective To explore the therapeutic effect of cupping and neo-auxiliary moxibustion on amenorrhea. Methods A total of 80 patients with amenorrhea admitted to the Yangzhou Hospital of Traditional Chinese Medicine from January 2019 to January 2022 were selected as the research objects and divided into the control group and the observation group according to the random number table method, with 40 cases in each group. The control group was treated with Chinese patent medicine, while the observation group was treated with cupping combined with new-auxiliary moxibustion. The course of treatment in both groups was 21 days. The clinical efficacy, changes of TCM syndrome scores before and after treatment, blood hormone levels before and after treatment and average time of menstruation were compared between the two groups. Results After treatment, the total effective rate of observation group was higher than that of control group, and the difference was statistically significant (P<0.05). Before treatment, there were no significant differences in the indexes of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T) and LH/FSH between the two groups (P>0.05). After treatment, the levels of LH, T, E₂ and LH/FSH in the two groups were decreased, and the levels of FSH were higher than those before treatment. The levels of LH, T, E₂ and LH/FSH in the observation group were lower than those in the control group, and the levels of FSH were higher than those in the control group, and the differences were statistically significant (P<0.05). Before treatment, there was no significant difference in the scores of TCM syndrome between the two groups (P>0.05). After treatment, the scores of each TCM syndrome in the two groups were lower than those before treatment, and the scores of each TCM syndrome in the observation group were lower than those in the control group, and the differences were statistically significant (P<0.05). After treatment, the average menstrual cycle of the observation group was longer than that of the control group, and the difference was statistically significant (P<0.05). Conclusion Cupping combined with Xinpu moxibustion in the treatment of amenorrhea can effectively regulate the blood hormone level and relieve the clinical symptoms. The clinical effect is remarkable and worthy of clinical application.

Key words: cupping, neoadjuvant moxibustion, menstrual arrest, clinical efficacy, hormone level, TCM syndrome score