Abstract: Objective To observe the clinical efficacy of Guizhi Fuling Xiaozheng decoction combined with western medicine methotrexate and mifepristone in the treatment of undamaged ectopic pregnancy. Method 96 patients with intact ectopic pregnancy in Qujing maternal and child health hospital from January 2021 to October 2021 were randomly divided into treatment group and control group; The control group was treated with methotrexate and mifepristone, and the treatment group was treated with methotrexate and mifepristone combined with Guizhi Fuling Xiaozheng decoction.The therapeutic dffects of the two groups were compared. Result The total effective rate in the treatment group was significantly higher than in the control group (P<0.05) β- Time and blood when hCG decreased more than 1/2 β- The time of hCG turning negative, the time of absorption reduction of ectopic pregnancy mass more than 1/2 and the time of hospitalization in the control group were shorter than those in the control group (P<0.05). Conclusion Guizhi Fuling Xiaozheng decoction combined with western medicine methotrexate and mifepristone has a significant clinical effect in the treatment of unruptured ectopic pregnancy and can significantly reduce blood pressure β- HCG value, accelerate the absorption of ectopic pregnancy mass, quickly improve clinical symptoms, improve clinical cure rate, shorten the course of disease, and reduce the tadverse effects of drugs.

Key words: Ectopic pregn, Guizhi Fuling Xiaozheng decoction, methotrexate, mifepristone