Abstract: Objective To study the clinical effect of Hanxia Baijiu Tianma Tang combined with Rosuvastatin in the treatment of carotid atherosclerotic plaque formation. Methods A total of 60 patients with carotid atherosclerotic plaque formation were selected, and according to the principle of randomized controlled grouping, 30 patients belonged to the control group and 30 to the observation group; The control group received Rosuvastatin, and the observation group received Rosuvastatin combined with Hanxia Baijiu Tianma Tang , The two groups were administered for four consecutive weeks, and the levels of lipid indexes [blood total cholesterol (TC), low-density lipoprotein cholesterol( LDL-C), Triglycerides (TG)], carotid plaque, Crouse points, and Chinese medicine symptoms were observed before and after the treatment. The clinical efficacy was evaluated by observing the levels of blood lipid indexes (blood TC, LDL-C, TG), carotid plaque, Crouse's score, and TCM symptom scores before and after treatment. Results After the intervention, the lipid index of the two groups was lower than that before the intervention, and the difference was statistically significant （P<0.05), and the lipid index of the observation group was lower than that of the control group, and the difference was statistically significant （P<0.05). After the intervention, the carotid Crouse points of the two groups were lower than before the intervention, and the difference was not statistically significant （P>0.05), and the carotid Crouse points of the observation group were lower than those of the control group, and the difference was not statistically significant （P>0.05). After the intervention, the TCM Crouse points of the two groups were lower than those before the intervention, and the difference was statistically significant （P<0.05), and the TCM Crouse points of the observation group were lower than those of the control group, and the difference was statistically significant （P<0.05). The total effective rate of treatment in the observation group was 93.33%, which was higher than the total effective rate of treatment in the control group of 66.67%, and the difference was statistically significant （P<0.05). Conclusion Combined treatment of carotid atherosclerotic plaques with Hanxia Baijiu Tianma Tang and Rosuvastatin has significant efficacy in the regulation of lipid metabolism and the alleviation of patients' clinical symptoms.

Key words: Banxia Baizhu Tianma Decoction, Rosuvastatin, carotid atherosclerotic plaque