Abstract: The theory of“homotherapy for heteropathy”is the essence of traditional Chinese medicine theory.Professor Liu Wanli treated the upper digestive tract reflux disease from the theory of“homotherapy for heteropathy”.He believed that liver and gallbladder dysfunction, spleen and stomach disharmony is the basic pathogenesis of the disease,and the obstruction of qi and blood runs through the beginning and end of the disease.Professor Liu took the principle of treating reflux diseases by lowering adverse reactions and stomachand relieving depression. He formulated "Jiangni soup" and "Tongjiang mixture", which have the effects of soothing the liver and clearing heat, eliminating dampness and phlegm, suppressing acid and protecting the stomach, regulating qi and calming the adverse-rising energy, and have goodclinical effect.

Key words: homotherapy for heteropathy, upper gastrointestinal tract reflux disease, passdown, depression, experience