Abstract: Objective To investigate the effect of combined use of oxytocin and Xinmupei on postpartum hemorrhage during cesarean section of scarred uterus. Methods From January 2020 to January 2022, 81 patients with scarred uterus undergoing cesarean section in Xinyu People's Hospital were selected as the research objects. According to the random number table method, they were divided into group A, group B and group C, 27 cases in each group. Group A was given oxytocin, group B was given intramuscular injection of Xinmupei on the basis of group A, and group C was given intramuscular injection of Xinmupei on the basis of group A. The differences in postpartum hemorrhage (postpartum hemorrhage volume in 2 hours, postpartum hemorrhage volume in 24 hours, postpartum hemorrhage rate, blood transfusion rate) among the three groups were analyzed; the changes of blood routine related indicators [red blood cell (RBC) and hemoglobin (HGB)] before and 2 hours after delivery were compared among the three groups; the differences in the incidence of adverse drug reactions within 48 hours after surgery were compared among the three groups. Results The postpartum hemorrhage volume, 24 h postpartum hemorrhage volume, postpartum hemorrhage rate and blood transfusion rate in groups B and C were lower than those in group A (P<0.05), there was no significant difference in the amount of postpartum hemorrhage at 2 h, the amount of postpartum hemorrhage at 24 h, the rate of postpartum hemorrhage, and the rate of blood transfusion between the two groups (P>0.05). Significantly increased (P<0.05), and groups B and C were significantly higher than group A at the same period (P<0.05), and there was no significant difference in RBC levels between groups B and C at 2 h postpartum (P>0.05). At 2 h postpartum compared with prepartum, HGB in the three groups was significantly decreased (P<0.05), but there was significant difference in the degree of HGB decline in groups B and C compared with group A (P<0.05), and there was no difference in HGB levels between groups B and C. Statistical significance (P>0.05); within 48 hours after operation, there was no significant difference in the incidence of adverse drug reactions among the three groups (P>0.05). Conclusion The application of oxytocin combined with Xinmupei in cesarean section of scarred uterus can effectively reduce the postoperative bleeding volume and improve the levels of RBC and HGB in patients. It is beneficial to its prognosis recovery.

Key words: scarred uterus, cesarean section, oxytocin, Xinmupei, postpartum hemorrhage