半夏白术天麻汤联合瑞舒伐他汀治疗颈动脉粥样硬化斑块的临床疗效观察

摘要/Abstract

摘要： 目的研究半夏白术天麻汤与瑞舒伐他汀联合治疗颈动脉粥样硬化斑块的临床疗效。方法选取2023年9月—2023年12月六安市中医院门诊和住院的辨证为风痰阻络证型的颈动脉粥样硬化斑块的患者60例,按照随机数表法,将其分为对照组和观察组,各30例,对照组单予以瑞舒伐他汀治疗,观察组在予以瑞舒伐他汀的基础上,加以半夏白术天麻汤治疗,两组均连续治疗4周,通过观察两组治疗前后血脂指标[血总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（Triglycerides,TG）]、颈动脉斑块Crouse积分以及中医证候积分去评估临床疗效。结果干预后,两组的血脂指标低于干预前,差异有统计学意义（P<0.05）,观察组的血脂指标低于对照组,差异有统计学意义（P<0.05）。干预后,两组的颈动脉Crouse积分低于干预前,差异无统计学意义（P>0.05）,观察组的颈动脉Crouse积分低于对照组,差异无统计学意义（P>0.05）。干预后,两组的中医证候积分低于干预前,差异有统计学意义（P<0.05）,观察组的中医证候积分低于对照组,差异有统计学意义（P<0.05）。观察组的治疗总有效率为93.33%,高于对照组的治疗总有效率（66.67%）,差异有统计学意义（P<0.05）。结论半夏白术天麻汤与瑞舒伐他汀联合治疗颈动脉粥样硬化斑块,在血脂代谢,临床症状缓解方面,具有明显疗效。

关键词: 半夏白术天麻汤, 瑞舒伐他汀, 颈动脉粥样硬化斑块

Abstract: Objective To study the clinical effect of Hanxia Baijiu Tianma Tang combined with Rosuvastatin in the treatment of carotid atherosclerotic plaque formation. Methods A total of 60 patients with carotid atherosclerotic plaque formation were selected, and according to the principle of randomized controlled grouping, 30 patients belonged to the control group and 30 to the observation group; The control group received Rosuvastatin, and the observation group received Rosuvastatin combined with Hanxia Baijiu Tianma Tang , The two groups were administered for four consecutive weeks, and the levels of lipid indexes [blood total cholesterol (TC), low-density lipoprotein cholesterol( LDL-C), Triglycerides (TG)], carotid plaque, Crouse points, and Chinese medicine symptoms were observed before and after the treatment. The clinical efficacy was evaluated by observing the levels of blood lipid indexes (blood TC, LDL-C, TG), carotid plaque, Crouse's score, and TCM symptom scores before and after treatment. Results After the intervention, the lipid index of the two groups was lower than that before the intervention, and the difference was statistically significant （P<0.05), and the lipid index of the observation group was lower than that of the control group, and the difference was statistically significant （P<0.05). After the intervention, the carotid Crouse points of the two groups were lower than before the intervention, and the difference was not statistically significant （P>0.05), and the carotid Crouse points of the observation group were lower than those of the control group, and the difference was not statistically significant （P>0.05). After the intervention, the TCM Crouse points of the two groups were lower than those before the intervention, and the difference was statistically significant （P<0.05), and the TCM Crouse points of the observation group were lower than those of the control group, and the difference was statistically significant （P<0.05). The total effective rate of treatment in the observation group was 93.33%, which was higher than the total effective rate of treatment in the control group of 66.67%, and the difference was statistically significant （P<0.05). Conclusion Combined treatment of carotid atherosclerotic plaques with Hanxia Baijiu Tianma Tang and Rosuvastatin has significant efficacy in the regulation of lipid metabolism and the alleviation of patients' clinical symptoms.

Key words: Banxia Baizhu Tianma Decoction, Rosuvastatin, carotid atherosclerotic plaque

中图分类号:

R259

陈艳群, 孙平, 杨言府. 半夏白术天麻汤联合瑞舒伐他汀治疗颈动脉粥样硬化斑块的临床疗效观察[J]. 中华养生保健, 2025, 43(4): 20-23.

CHEN Yan-qun, SUN Ping, YANG Yan-fu. Clinical Efficacy Observation of Banxia Baizhu Tianma Decoction Combined with Rosuvastatin in Treating Patients with Carotid Atherosclerotic Plaques[J]. ZHONGHUA YANGSHENG BAOJIAN, 2025, 43(4): 20-23.

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