急诊洗胃联合血液净化对精神类药物中毒的治疗分析

中华养生保健 ›› 2024, Vol. 42 ›› Issue (8): 1-4.

• 论著 • 下一篇

急诊洗胃联合血液净化对精神类药物中毒的治疗分析

张潇月, 李探, 邵龙刚, 刘克琴^*

南京中医药大学第二附属医院（江苏省第二中医院)急诊科,江苏南京,210000

出版日期:2024-04-16 发布日期:2024-04-08
通讯作者: ^* 刘克琴,E-mail：15312019157@163.com。
作者简介:张潇月（1989—）,女,汉族,籍贯：四川省广安市,硕士研究生,主治医师,研究方向：药物中毒、脓毒症。
基金资助:
江苏省中医药科技发展计划项目（MS2022042、MS2022036）; 南京市中西医结合疫病研究中心科研基金资助项目（NCMIC-2022-08）; 南京中医药大学自然科学基金项目（XZR2020052）

Analysis of Emergency Gastric Lavage Combined with Blood Purification

ZHANG Xiao-yue, LI Tan, SHAO Long-gang, LIU Ke-qin^*

Department of Emergency, the Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine (Jiangsu Second Hospital of Traditional Chinese Medicine), Nanjing Jiangsu 210000, China

Online:2024-04-16 Published:2024-04-08

摘要/Abstract

摘要： 目的探讨急诊洗胃和血液净化对急性重度精神类药物中毒的治疗价值。方法回顾性收集2017年1月—2023年1月江苏省第二中医院急诊科收治的85例急性重度精神类药物中毒患者的病历资料,根据患者的治疗方案分为保守治疗组、洗胃组、血液净化组、洗胃+血液净化组。收集各组患者的基本资料、洗胃及血液净化相关并发症发生率、预后相关指标等。结果收集的85例患者年龄分布在18~92岁,各组间的基线资料比较,差异无统计学意义（P>0.05）。与保守治疗组和血液净化组相比较,洗胃组和洗胃+血液净化组的洗胃相关并发症发生率显著升高,差异有统计学意义（P<0.05）;与保守治疗组和洗胃组相比较,血液净化组和洗胃+血液净化组的坠积性肺炎、心脑血管意外的发生率更低,差异有统计学意义（P<0.05）。血液净化组和洗胃+血液净化组预后相关指标较保守治疗组和洗胃组均显著下降,但治疗费用并没有显著增加,差异均有统计学意义（P<0.05）。结论在急性重度精神类药物中毒的治疗中,洗胃往往不能获得良好收益,反而增加洗胃相关并发症的发生率,而早期的血液净化治疗能够显著改善患者预后,且不增加住院总费用,安全性较好,值得临床应用。

关键词: 急性中毒, 精神类药物中毒, 急诊洗胃, 血液净化

Abstract: Objective To investigate the value of emergency gastric lavage and blood purification for acute severe psychiatric poisoning. Methods A total of 85 patients with acute severe psychotic drug poisoning admitted to the emergency department of Jiangsu Second Middle School Hospital from January 2017 to January 2023 were collected retrospectively. According to the treatment plan of the patients, they were divided into conservative treatment group, gastric lavage group, blood purification group, gastric lavage and blood purification group.Basic data of each group, incidence of complications related to gastric lavage and blood purification, and prognosis related indicators of each group were collected. Results The 85 patients were 18 to 92 years, and there was no significant difference in baseline data between groups (P>0.05). Compared with the conservative treatment and blood purification groups, the incidence of gastric lavage related complications in the gastric lavage and gastric lavage and blood purification group significantly increased(P<0.05), the incidence of falling pneumonia and cardiovascular and cerebrovascular accidents were lower in the conservative treatment and gastric lavage group(P<0.05). The prognosis related indicators in the blood purification group and gastric lavage and blood purification group decreased significantly compared with the conservative treatment group and gastric lavage group, but the treatment cost did not increase significantly, and the difference was statistically significant (P<0.05). Conclusion In the treatment of acute severe psychiatric drug poisoning, gastric lavage often cannot get good benefits, but increased the complications of gastric lavage, and blood purification treatment can significantly improve patient outcomes without increasing the total hospitalization cost, and does not increase the total cost of hospital, safety is better, and it deserves being recommended in clinical recommendation.

Key words: acute poisoning, psychotic drug poisoning, emergency gastric lavage, blood purification

中图分类号:

R459.7

张潇月, 李探, 邵龙刚, 刘克琴. 急诊洗胃联合血液净化对精神类药物中毒的治疗分析[J]. 中华养生保健, 2024, 42(8): 1-4.

ZHANG Xiao-yue, LI Tan, SHAO Long-gang, LIU Ke-qin. Analysis of Emergency Gastric Lavage Combined with Blood Purification[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(8): 1-4.

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急诊洗胃联合血液净化对精神类药物中毒的治疗分析

Analysis of Emergency Gastric Lavage Combined with Blood Purification

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