红蓝光联合系统药物治疗带状疱疹的安全性及有效性分析

中华养生保健 ›› 2024, Vol. 42 ›› Issue (6): 40-44.

红蓝光联合系统药物治疗带状疱疹的安全性及有效性分析

肖子浩¹, 傅伟², 黄登霞³, 刘德武^4,*

1.贵州中医药大学第二临床医学院,贵州贵阳,550003;
2.广州中医药大学第七临床医学院,广东广州,510006;
3.玉山县黄家驷医院皮肤科,江西上饶,334700;
4.贵州中医药大学第二附属医院肛肠科,贵州贵阳,550003

出版日期:2024-03-16 发布日期:2024-03-07
通讯作者: ^*刘德武,E-mail：516638785@qq.com。
作者简介:肖子浩（1996—）,男,汉族,籍贯：江西省上饶市,硕士研究在读,住院医师,研究方向：中医药诊治肛肠疾病。
基金资助:
国家自然科学基金地区科学基金项目（82160909）; 贵州省中医药管理局项目（QZYY-2023-045）

Analysis of Safety and Efficacy of Red and Blue Light Combined with Systemic Drugs in the Treatment of Herpes Zoster

XIAO Zi-hao¹, FU Wei², HUANG Deng-xia³, LIU De-wu^4,*

1. The Second Clinical Medical College of Guizhou University of Traditional Chinese Medicine, Guiyang Guizhou 550003, China;
2. The Seventh Clinical College of Guangzhou University of Chinese Medicine, Guangzhou Guangdong 510006, China;
3. Dermatology Department of Huangshi Hospital in Yushan County, Shangrao Jiangxi 334700, China;
4. Department of Proctology, Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang Guizhou 550003, China

Online:2024-03-16 Published:2024-03-07

摘要/Abstract

摘要： 目的利用Meta分析观察红蓝光联合系统药物治疗带状疱疹的临床有效性和安全性。方法检索the Cochrane Library、EMbase 数据库、Pubmed数据库、中国生物医学文献数据库、CNKI（China national knowledge infrastructure）数据库、维普数据库、万方数据库,纳入红蓝光联合系统药物治疗带状疱疹的随机对照治疗（randomized controlled trial,RCT）,并进行方法学质量评价,采用RevMan 5.4软件进行统计分析。结果 8篇RCT文献纳入本项研究,累计病例1 240例。Meta分析结果显示红蓝光联合系统药物治疗带状疱疹总有效率（OR=4.92,95%CI：2.95~8.21,P<0.00001）、痊愈率（OR=2.17,95%CI：1.66~2.85,P<0.00001）、水疱消退时间（MD=-1.16,95%CI：-1.33~-0.98,P<0.00001）、结痂时间（MD=-1.47,95%CI：-1.80~-1.14,P<0.00001）、疼痛缓解时间（MD=-2.05,95%CI：-2.54~-1.56,P<0.00001）效果明显优于单纯使用基础药物组,差异有统计学意义（P<0.05）。结论红蓝光联合系统药物治疗带状疱疹疗效确切,优于系统药物组,是光电联合药物治疗带状疱疹的有效方法。

关键词: 红蓝光, 带状疱疹, 安全性, 有效性

Abstract: Objective To evaluate the clinical efficacy and safety of red and blue light combined system drug in the treatment of herpes zoster by meta-analysis. Methods The Cochrane Library, EMbase database, Pubmed database, China Biomedical Literature Database and China national knowledge infrastructure (CNKI) were searchedA randomized controlled trial (RCT) about red and blue light combined systemic drug therapy for herpes zoster was included, and methodological quality was evaluated, and statistical analysis was performed using RevMan 5.4 software, according to the database, Wip database, and Wanfang database. Results 8 RCT articles were included in this study, with a total of 1240 cases. The results of meta-analysis showed that the total effective rate (OR=4.92, 95%CI:2.95-8.21, P<0.00001) and recovery rate (OR=2.17, 95%CI:1.66-2.85, P<0.00001), vesicle regression time (MD=-1.16, 95%CI:-1.33-0.98, P<0.00001), scab time (MD=-1.47, 95%CI:-1.80-1.14, P<0.00001), pain relief time (MD=-2.05, 95%CI:-2.54-1.56, P<0.00001), and the effect was significantly better than that of the group using basic drugs alone, the difference was statistically significant (P<0.05). Conclusion The combination of red and blue light system drug treatment of herpes zoster is effective, and better than the system drug group, is an effective method of photoelectric combination drug treatment of herpes zoster.

Key words: red and blue light, herpes zoster, security, effectiveness

中图分类号:

R266

肖子浩, 傅伟, 黄登霞, 刘德武. 红蓝光联合系统药物治疗带状疱疹的安全性及有效性分析[J]. 中华养生保健, 2024, 42(6): 40-44.

XIAO Zi-hao, FU Wei, HUANG Deng-xia, LIU De-wu. Analysis of Safety and Efficacy of Red and Blue Light Combined with Systemic Drugs in the Treatment of Herpes Zoster[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(6): 40-44.

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