超声引导下微波消融与传统甲状腺手术对甲状腺良性肿瘤的治疗效果分析

摘要/Abstract

摘要： 目的探析对甲状腺良性肿瘤患者应用超声引导下微波消融与传统甲状腺手术治疗的临床效果差异。方法选取2020年1月—2023年1月济宁市第二人民医院收治的80例确诊为甲状腺良性肿瘤且符合手术指征的患者作为研究对象,以患者手术治疗方案差异将其分为传统组和观察组,每组40例。传统组患者应用传统甲状腺手术治疗,观察组患者应用超声引导下微波消融术治疗。比较两组患者治疗效果、手术临床指标、并发症发生情况以及甲状腺激素指标情况。结果观察组患者治疗总有效率高于传统组,差异有统计学意义（P<0.05）。观察组患者手术时间、住院时间均短于传统组,术中出血量少于传统组,差异有统计学意义（P<0.05）。观察组患者术后相关并发症发生率低于传统组,差异有统计学意义（P<0.05）。术前,两组患者甲状腺血清指标[血清游离三碘甲状腺原氨酸（FT3）、血清游离四碘甲状腺原氨酸（FT4）、促甲状腺激素（TSH）]水平比较,差异无统计学意义（P>0.05）;术后,观察组患者FT3、FT4指标水平高于传统组,TSH指标水平低于传统组,差异有统计学意义（P<0.05）。结论超声引导下微波消融术治疗甲状腺良性肿瘤患者,疗效及安全性更满足临床需求,减少可能对患者产生的不良影响。

关键词: 超声, 微波消融术, 传统手术, 甲状腺, 良性肿瘤

Abstract: Objective To explore the difference of clinical effect between ultrasound-guided microwave ablation and traditional thyroid surgery in the treatment of thyroid benign tumor. Methods Eighty patients with thyroid benign tumor diagnosed by general surgery department of the Second People's Hospital of Jining City from January 2020 to January 2023 and conforming to the surgical indications were included as the analysis objects. Based on the difference of surgical treatment schemes,the patients were divided into the traditional group and the observation group, with 40 cases in each group.The traditional group patients were treated with traditional thyroid surgery,while the observation group patients were treated with ultrasound guided microwave ablation.The therapeutic effect was evaluated from the therapeutic effect,clinical indicators, complications and Thyroid hormones indicators of the two types of surgery. Results The effective rate of thyroid benign tumor treatment in the observation group was higher than that in the traditional group, with a statistically significant difference (P<0.05). In terms of surgical indicators, the observation group had shorter surgical time and hospital stay than the traditional group, and the intraoperative blood output was lower than the traditional group,with a statistically significant difference (P<0.05). The incidence of postoperative complications in the observation group was lower than that in the traditional group, and the difference was statistically significant (P<0.05). There was no statistically significant difference in the detection of serum free Triiodothyronine (FT3), serum free Tetraiodothyronine(FT4), and Thyroid-stimulating hormone (TSH) before operation between the two groups. The FT3 and FT4 indexes of patients in the observation group after operation were higher than those in the traditional group, and the TSH indexes were lower than those in the traditional group,with a statistically significant difference (P<0.05). Conclusion The efficacy and safety of ultrasound-guided microwave ablation for patients with thyroid Benign tumor can meet the clinical needs and reduce the possible adverse effects on patients.

Key words: ultrasound, microwave ablation, traditional surgery, thyroid gland, benign tumor

中图分类号:

R653

张宗显. 超声引导下微波消融与传统甲状腺手术对甲状腺良性肿瘤的治疗效果分析[J]. 中华养生保健, 2024, 42(5): 48-50.

ZHANG Zong-xian. Analysis of Therapeutic Effect of Ultrasound-Guided Microwave Ablation and Traditional Thyroid Surgery on Thyroid Benign Tumor[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(5): 48-50.

参考文献

[1] 丛仔红,张元会.超声引导喉上神经阻滞联合颈神经通路阻滞在甲状腺癌根治术中的应用研究[J].陕西医学杂志,2022,51(11):1408-1411.
[2] 王晶,刘易婷,刘哲.超声引导下颈部淋巴结细针穿刺对甲状腺癌131I治疗后复发的诊断价值[J].癌症进展,2022,20(3):249-251,273.
[3] 李颉,朱伟谕,梁龙飞,等.超声引导下纳米炭定位在甲状腺癌再次淋巴结清扫术中的应用价值[J].癌症进展,2020,18(9):887-890.
[4] 黄建新,陈薇,郑建华,等.超声引导下细针穿刺结合BRAF V600E检测在诊断甲状腺癌的价值[J].医学影像学杂志,2021,31(1):126-129.
[5] 中华人民共和国国家卫生健康委员会.甲状腺癌诊疗规范(2018年版)[J]. 中华普通外科学文献:电子版,2019,13(1):15.
[6] 丁春棉,张丹华,丁丽凡.不同手术方式治疗分化型甲状腺癌的临床疗效及其影响因素[J].实用癌症杂志,2023,38(1):82-84,88.
[7] 胡晓晨,冯苗,曾倩.多功能保留颈清扫术治疗cN1b期分化型甲状腺癌患者的疗效及对复发和并发症的影响[J].癌症进展,2022,20(19):1990-1992.
[8] 常得丰,沙倩羽,徐忠庆,等.探究免充气经腋窝入路腔镜手术治疗单侧甲状腺癌的临床疗效与安全性[J].中国现代药物应用,2022,16(3):65-67.
[9] 何兴政. 甲状腺全切除术与近全切除术治疗甲状腺癌疗效及安全性比较研究[J].中国医学文摘(耳鼻咽喉科学),2022,36(3):96-97,109.
[10] 汪鑫,武晓娜,曹力钒,等.改良Miccoli手术治疗分化型甲状腺癌的疗效及术后复发的相关因素分析[J].癌症进展,2020,18(2):172-175.
[11] 蒋玉欢,何本超,郑志刚,等.改良Miccoli微创术联合术后DC-CIK治疗甲状腺癌疗效及对患者血清Gal-3、sIL-2R水平的影响[J].陕西医学杂志,2020,49(11):1417-1421.
[12] 李涛,焦良和,朱正才,等.三种手术方式治疗cT1N0期甲状腺癌的近期疗效及安全性比较[J].中华普外科手术学杂志(电子版),2020,14(6):624-627.
[13] 赵富利,康艳丽,马瑜瑾,等.TSH抑制疗法对老年甲状腺癌患者甲状腺全切除术后的疗效分析及对血清Tg、TSH、CEA水平的影响[J].实用癌症杂志,2021,36(12):1970-1973.
[14] 王小龙,杨文翠,李航.不同手术方法治疗甲状腺癌的疗效及其对患者炎症应激反应的影响[J].海南医学,2020,31(17):2207-2210.
[15] 吴文华,郭午红,周艳,等.经超声引导下微波消融与传统甲状腺手术治疗对甲状腺良性肿瘤患者甲状腺功能的影响[J].中国医疗器械信息,2022,28(16):35-37.