前胡竹叶汤治疗对老年顽固性咳嗽患者炎症因子水平、肺功能及生活质量的影响

中华养生保健 ›› 2024, Vol. 42 ›› Issue (24): 47-51.

前胡竹叶汤治疗对老年顽固性咳嗽患者炎症因子水平、肺功能及生活质量的影响

丁杰¹, 徐志东², 王振亚³, 姜利国^3,*

1.河北省围场满族蒙古族自治县山湾子乡中心卫生院,河北承德,068459;
2.河北省围场满族蒙古族自治县半截塔镇中心卫生院,河北承德,068458;
3.河北省围场满族蒙古族自治县中医院中医科,河北承德,068459

出版日期:2024-12-16 发布日期:2024-12-13
通讯作者: ^*姜利国,E-mail：wzy841122@163.com。
作者简介:丁杰（1975—）,男,满族,籍贯：河北省承德市,本科,副主任中医师,研究方向：肺病的经方治疗。

Study on the Clinical Efficacy of Qianhu Zhuye Decoction in the Treatment of Stubborn Cough in the Elderly

DING Jie¹, XU Zhi-dong², WANG Zhen-ya³, JIANG Li-guo^3,*

1. Central Health Center of Shanwanzi Township, Weichang Manchu and Mongolian Autonomous County, Hebei Province, Chengde Hebei 068459, China;
2. Central Health Center of Banjieta Town, Weichang Manchu and Mongolian Autonomous County, Hebei Province, Chengde Hebei 068458, China;
3. Traditional Chinese Medicine Hospital of Weichang Manchu and Mongolian Autonomous County, Hebei Province, Chengde Hebei 068459, China

Online:2024-12-16 Published:2024-12-13

摘要/Abstract

摘要： 目的探讨前胡竹叶汤治疗对老年顽固性咳嗽患者炎症因子水平、肺功能及生活质量的影响。方法选取河北省围场满族蒙古族自治县山湾子乡中心卫生院于2022年1月—2023年1月收治的老年顽固性咳嗽患者120例为研究对象。采用随机数表法分为对照组（60例）和观察组（60例）。对照组和观察组分别采用常规西药治疗和前胡竹叶汤治疗。对比两组治疗前和治疗后的炎症因子水平、肺功能指标、生活质量变化情况。结果治疗前两组组间对比,白介素-1（IL-1）、肿瘤坏死因子-α（TNF-α）、白介素-6（IL-6）水平差异无统计学意义（P>0.05）,治疗后与对照组相比,观察组的IL-1、TNF-α、IL-6水平更低（P<0.05）;治疗前两组组间对比,第1秒用力呼气量（FEV₁）、第1秒用力呼气量/用力肺活量（FEV₁/FVC）、最大呼气流量（PEF）差异无统计学意义（P>0.05）,治疗后与对照组相比,观察组的FEV₁、FEV₁/FVC、PEF更高（P<0.05）;治疗前两组组间对比,健康调查简表-36（SF-36）评分差异无统计学意义（P>0.05）,治疗后与对照组相比,观察组的SF-36评分更高（P<0.05）。结论前胡竹叶汤治疗老年顽固性咳嗽,可有效降低患者机体炎症因子水平,改善肺功能,提高生活质量。

关键词: 前胡竹叶汤, 老年顽固性咳嗽, 炎症因子, 肺功能, 生活质量

Abstract: Objective To explore the effects of Qianhu Zhuye Tang of inflammatory factor levels, lung function and quality of life on stubborn cough in the elderly patients. Methods 120 cases of stubborn cough in the elderly patients were admitted to Central Health Center of Shanwanzi Township, Weichang Manchu and Mongolian Autonomous County, Hebei Province from January 2022 to January 2023 were seclect, Divided into control group (60cases) and observation group (60cases) using a random number table method. Control group and observation group were treated with conventional western medicine and qianhu zhuye decoction. The changes of inflammatory factor levels indexes, lung function indexes and quality of life were compared between two groups before and after treatment. Results There was no significant difference in the levels of interleukin-1 (IL-1), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) between the two groups before treatment (P>0.05). Compared with the control group after treatment, The observation group had lower levels of IL-1, TNF-α and IL-6 (P<0.05). There was no significant difference in the Forced expiratory volume in the first second (FEV₁), FEV1/forced vital capacity (FVC) and peak expiratory flow (PEF) between the two groups before treatment (P>0.05). Compared with the control group after treatment, the observation group had higher levels of FEV₁, FEV₁/FVC and PEF (P<0.05); There was no significant difference of short-form health survey-36 (SF-36) scores between the two groups before treatment (P>0.05), Compared with the control group after treatment, The observation group had a higher SF-36 scores (P<0.05). Conclusion Qianhu zhuye decoction in the treatment of stubborn cough in the elderly, which can effectively reduce inflammatory factors level in patients, improve lung function and the quality of life.

Key words: Qianhu zhuye decoction, stubborn cough in the elderly, inflammatory factor, lung function, quality of life

中图分类号:

R259

丁杰, 徐志东, 王振亚, 姜利国. 前胡竹叶汤治疗对老年顽固性咳嗽患者炎症因子水平、肺功能及生活质量的影响[J]. 中华养生保健, 2024, 42(24): 47-51.

DING Jie, XU Zhi-dong, WANG Zhen-ya, JIANG Li-guo. Study on the Clinical Efficacy of Qianhu Zhuye Decoction in the Treatment of Stubborn Cough in the Elderly[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(24): 47-51.

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