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中华养生保健 ›› 2024, Vol. 42 ›› Issue (21): 181-184.

• 经验交流 • 上一篇    下一篇

阴道炎五联检联合显微镜镜检在不孕症女性阴道炎诊断的价值

贺伟   

  1. 上海市第一人民医院酒泉医院生殖医学科,甘肃 酒泉,735000
  • 出版日期:2024-11-01 发布日期:2024-10-24
  • 作者简介:贺伟(1977—) ,女,汉族,籍贯:山西省忻州市 ,本科,副主任检验师,研究方向:不孕不育的实验室诊断及人类辅助生殖技术。

The Value of Five Tests for Penta-test for Vaginitis Combined with Microscopic Microscopy in the Diagnosis of Vaginitis in Infertile Women

HE Wei   

  1. Department of reproductive medicine , Jiuquan People's Hospital, Jiuquan Gansu 735000, China
  • Online:2024-11-01 Published:2024-10-24

摘要: 目的 探讨阴道炎五联检(五联检)联合显微镜镜检(镜检)在不孕症女性阴道炎诊断中的应用价值。方法 选取2020年1月—2023年12月在上海市第一人民医院酒泉医院就诊的226例疑似阴道炎的不孕症女性患者作为研究对象,均接受阴道分泌物显微镜镜检(对细菌、滴虫、念珠菌、白细胞计数)与阴道炎五联检(采用五联试剂盒检测标本6项指标:pH、白细胞酯酶、过氧化氢、脯氨酸氨基肽酶、唾液酸苷酶、乙酰氨基葡萄糖苷酶),比较镜检、五联检和联合检测对阴道炎的阳性检出率。比较3种不同检测方法对阴道炎的诊断效能和对阴道炎不同病原菌的检出率。结果 226例疑似阴道炎的不孕症女性患者中确诊阴道炎72例,检出率为31.86%,镜检法检出阳性49例,五联检法检出阳性60例,联合检测检出阳性68例,联合检测的敏感度、特异度和准确度均明显高于镜检法与五联检法,差异有统计学意义(P<0.05)。联合检测、五联法、镜检对细菌、霉菌、滴虫的检出率均明显高于单独一项检测,差异有统计学意义(P<0.05)。镜检法霉菌检出率高于五联检。联合检测、五联法对细菌、滴虫的检出率比较,差异无统计学意义(P>0.05)。结论 阴道炎五联检联合显微镜镜检可提高对阴道炎的检出阳性率和阴道炎不同病原菌的检出率,诊断效能较高。

关键词: 女性不孕症, 阴道炎, 阴道炎五联检, 显微镜镜检, 诊断

Abstract: Objective To investigate the value of the penta-test(penta-test) for vaginitis combined with microscopic microscopy(microscopy) in the diagnosis of vaginitis in infertile women. Methods A total of 226 infertile female patients with suspected vaginitis attending Jiuquan People's Hospital from January 2020 to December 2023 were selected for the study, and all of them underwent microscopic microscopic examination of vaginal secretions (for bacterial, trichomonas, candida, and leukocyte counts) with the vaginitis penta-test (a penta-test kit was used to test the specimens for six indices: pH value, level of leukocyte esterase, hydrogen peroxide, and proline aminopeptidase, sialidase, and acetylaminoglucosidase), and compare the positive detection rates of microscopy, penta-test and the combined test for vaginitis. To compare the diagnostic efficacy of the three different tests for vaginitis and the detection rates of different pathogens of vaginitis. Results 226 seventy-two cases of vaginitis were diagnosed in infertile female patients with suspected vaginitis, with a detection rate of 31.86%. 49 cases were detected positively by the microscopic method, 60 cases were detected positively by the penta-test method, and 68 cases were detected positively by the combined test, and the sensitivity, specificity and accuracy of the combined test were significantly higher than that of the microscopic method and the penta-test method (P<0.05). The difference in the detection rate of bacteria and trichomonas was not statistically significant when comparing the detection rates of the combined test and the pentameric method (P>0.05). Conclusion Vaginitis 5 combined with microscopic examination can increase the positive detection rate of vaginitis and the detection rate of different pathogens of vaginitis, and the diagnostic efficacy is higher.

Key words: female infertility, vaginitis, penta-test for vaginitis, microscopic examination, diagnosis

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