甘油三酯葡萄糖指数联合尿pH对肾结石的影响分析

摘要/Abstract

摘要： 目的探索甘油三酯葡萄糖指数（TyG指数）和尿pH及两者联合对预测肾结石的价值。方法选取2022—2023年天府新区人民医院体检中心2 190例体检者作为研究对象,根据彩超结果将其分为结石组和非结石组。比较两组指标的差异,通过二分类logistic回归模型分析结石组的危险因素,并绘制受试者工作特征（ROC）曲线以评估TyG指数和尿pH值及两者联和对肾结石的预测能效。结果 2 190例对象中,结石组360例（16.4%）,将临床基线资料中有意义的变量进行logistic回归分析后得出,TyG指数和尿pH是肾结石独立危险因素。ROC曲线分析提示,TyG指数和尿pH及两者联合预测肾结石的曲线下面积分别为0.832、0.799和0.895。结论 TyG指数和尿pH对肾结石的发生具有较高的预测价值,且二者联合预测肾结石的发病上具有更高的能效性。

关键词: 肾结石, 甘油三酯葡萄糖指数, 尿pH

Abstract: Objective To explore the value of triglyceride glucose index ( TyG index ) and urine pH value and their combination in predicting renal calculi. Methods A total of 2 190 cases of medical checkups at the Physical Examination Center of People's Hospital of Tianfu New Area in 2022-2023 were selected as the study subjects, and they were divided into stone and non-stone groups according to the ultrasound results. According to the results of color Doppler ultrasound, they were divided into stone group and non-stone group. The differences between the two groups were compared. The risk factors of the stone group were analyzed by binary logistic regression model, and the receiver operating characteristic (ROC) curve was drawn to evaluate the predictive efficiency of TyG index and urine pH value and their combination for renal calculi. Results Among the 2 190 subjects, 360(16.4%) were in the stone group. After logistic regression analysis of meaningful variables in clinical baseline data, it was concluded that TyG index and urinary pH value were independent risk factors for renal calculi. ROC curve analysis showed that the area under the curve of TyG index, urine pH value and their combination in predicting renal calculi were 0.832,0.799 and 0.895, respectively. Conclusion TyG index and urine pH value have high predictive value for the occurrence of renal calculi, and the combination of the two has higher energy efficiency in predicting the incidence of renal calculi.

Key words: kidney stones, triglyceride glucose index, urine pH

中图分类号:

R692.4

陈锐, 翟超, 曾安军, 舒向晖, 樊清和, 彭志飞, 彭文希, 吴克, 唐多才. 甘油三酯葡萄糖指数联合尿pH对肾结石的影响分析[J]. 中华养生保健, 2024, 42(20): 12-16.

CHEN Rui, ZHAI Chao, ZENG An-jun, SHU Xiang-hui, FAN Qing-he, PENG Zhi-fei, PENG Wen-xi, WU Ke, TANG Duo-cai. Analysis of the Effect of Triglyceride Glucose Index Combined with Urinary pH Value on Renal Calculi[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(20): 12-16.

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