基于“药邪理论”浅析激素性股骨头坏死病机

摘要/Abstract

摘要： “药邪”为药物炮制或使用不当引起的人体生理生化功能紊乱。“激素性股骨头坏死”指高剂量激素导致股骨头活性成分死亡的病理过程。基于“药邪理论”,结合糖皮质激素对股骨头的不利影响,分析激素性股骨头坏死发生发展的病机;激素作为药邪,影响激素性股骨头坏死的病机归结为气血凝滞,气滞血瘀或津液失调,痰瘀互结,进而内舍脏腑,损肝脾肾,最终导致骨失濡养,久而坏死。治疗以行气、祛瘀、化痰、补肾为基本治法,除邪以安疾。基于此理论,为今后实验验证及临床治疗提供思路。

关键词: 中医, 药邪, 激素, 激素性股骨头坏死, 病机

Abstract: Medicine evil is the human physiological and biochemical dysfunction caused by the processing or improper use of drugs.Steroid-induced Necrosis of the Femoral Head " refers to the pathological process in which high doses of hormones lead to the death of the active components of the femoral head. Drawing upon the principles of the "Medicinal Toxins Theory" and acknowledging the detrimental effects of glucocorticoids on the femoral head, this study delves into the pathogenesis of steroid-induced necrosis of the femoral head through the lens of traditional Chinese medicine. Within this framework, hormones are viewed as medicinal toxins that play a significant role in influencing the development of steroid-induced necrosis. This influence is attributed to factors such as the stagnation of Qi and blood, the amalgamation of fluid imbalance, phlegm, and stasis, as well as internal organ impairment impacting the liver, spleen, and kidney, ultimately leading to bone malnutrition and necrosis over time.In terms of treatment, the focus lies on fundamental methods that involve promoting Qi circulation, dispelling blood stasis, resolving phlegm, and replenishing kidney function. The ultimate goal is to expel toxins and alleviate symptoms. This theory establishes a solid theoretical foundation for future experimental validation and clinical approaches.

Key words: traditional Chinese medicine, medicinal toxins, hormones, steroid-induced necrosis of the femoral head, pathogenesis.

中图分类号:

R274.9

周长安, 黄琼. 基于“药邪理论”浅析激素性股骨头坏死病机[J]. 中华养生保健, 2024, 42(2): 81-84.

ZHOU Chang-an, HUANG Qiong. Analyzing the Pathogenesis of Steroid-Induced Necrosis of the Femoral Head Based on the "Medicinal Toxins Theory"[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(2): 81-84.

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