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中华养生保健 ›› 2024, Vol. 42 ›› Issue (18): 1-4.

• 论著 •    下一篇

三黄四物汤治疗慢性宫颈炎的临床观察

李静1, 刘美芳1, 王有女1, 齐耀群1, 郭凤媛2,*   

  1. 1.九江学院附属医院药学部,江西 九江,332000;
    2.浔阳区人民医院药学部,江西 九江,332000
  • 出版日期:2024-09-16 发布日期:2024-09-04
  • 通讯作者: *郭凤媛,E-mail:ajing2008.cool@163.com。
  • 作者简介:李静(1989—),女,汉族,籍贯:江西省九江市,博士研究生,主管药师,研究方向:中药药理及临床药学。
  • 基金资助:
    九江市重点研发计划-指导性计划(S2022ZDYFN257); 江西省中医药管理局科技计划(2022B1032); 江西省卫生健康委科技计划(202212017)

Clinical Study on the Treatment of Chronic Cervicitis with San Huang Si Wu Decoction

LI Jing1, LIU Mei-fang1, WANG You-nv1, Qi1Yao-qun1, Guo Feng-yuan2,*   

  1. 1. Department of Pharmacy, Affiliated Hospital of Jiujiang University, jiujiang jiangxi, 332200, China;
    2. Department of Pharmacy, People's Hospital of Xunyang District, jiujiang jiangxi, 332200, China
  • Online:2024-09-16 Published:2024-09-04

摘要: 目的 评估三黄四物汤治疗慢性宫颈炎的效果。方法 选取2022年1月—2023年12月于九江学院附属医院就诊的80例慢性宫颈炎患者作为研究对象。依据随机数表法将其分为对照组(常规西医治疗)与观察组(在对照组基础上加用三黄四物汤治疗),比较两种治疗方案对患者临床疗效的影响,具体评估指标包括临床症状改善、中医证候积分、宫颈糜烂修复情况、血清炎症因子水平以及治疗相关的不良事件发生率。结果 治疗结束后,观察组总体有效率显著高于对照组,差异有统计学意义(P<0.05);观察组宫颈糜烂恢复至正常的比例显著高于对照组,差异有统计学意义(P<0.05);观察组中医证候积分及血清炎症因子水平均显著低于对照组,差异有统计学意义(P<0.05);观察组治疗相关不良事件发生率显著低于对照组,差异有统计学意义(P<0.05)。结论 三黄四物汤在治疗慢性宫颈炎方面显示出显著疗效,能有效促进宫颈糜烂修复,降低血清炎症因子水平,且具有较高的安全性。

关键词: 三黄四物汤, 慢性宫颈炎, 临床研究, 疗效, 安全性

Abstract: Objective This study aimed to evaluate the efficacy of San Huang Si Wu Tang in treating chronic cervicitis. Methods A randomized number table method was employed to select 80 patients with chronic cervicitis treated at the Affiliated Hospital of Jiujiang University from January 2022 to December 2023. Patients were randomly allocated to either the conventional Western medicine treatment group (control group) or the San Huang Si Wu Tang treatment group (Observation group) to compare the impact of the two treatment regimens on clinical efficacy. The evaluation indicators included improvement of clinical symptoms, Traditional Chinese Medicine (TCM) syndrome score, repair of cervical erosion, changes in serum inflammatory factor levels, and the incidence of treatment-related adverse events. Results The overall effectiveness rate of the experimental group was significantly higher than that of the control group, with a statistically significant difference (P<0.05). The proportion of cervical erosion recovery to normal in the experimental group was also significantly higher than that in the control group (P<0.05). Moreover, compared to the control group, the experimental group showed more significant improvements in TCM syndrome scores and reductions in serum inflammatory factor levels (P<0.05), with a lower incidence of treatment-related adverse events (P<0.05). Conclusion San Huang Si Wu Tang demonstrated significant therapeutic effects in treating chronic cervicitis, effectively promoting the repair of cervical erosion, reducing serum inflammatory factor levels, and possessing high safety.

Key words: San Huang Si Wu decoction, chronic cervicitis, clinical study, efficacy, safety

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