麝香保心丸联合β受体阻滞剂对冠心病合并室性早搏的应用效果及对心电图指标的影响

摘要/Abstract

摘要： 目的探讨麝香保心丸联合β受体阻滞剂对冠心病合并室性早搏的应用效果及对心电图指标的影响。方法选取2018年5月—2023年4月甘肃省定西市中医院收治的80例冠心病合并室性早搏患者作为研究对象,应用抽签法将其分为观察组与对照组,各40例。对照组采取常规β受体阻滞剂美托洛尔治疗,观察组在对照组治疗基础上增加麝香保心丸口服治疗。比较两组患者临床疗效、治疗前后心功能变化以及24 h动态心电图监测结果。结果观察组治疗总有效率明显高于对照组,差异有统计学意义（P<0.05）;治疗3个月后两组患者心室射血分数（LVEF）均升高,且观察组明显高于对照组,左心室收缩末期容积（LVESV）、左心室舒张末期容积（LVEDV）水平均降低,且观察组收缩末期容积（LVESV）、左心室舒张末期容积（LVEDV）水平低于对照组,差异均有统计学意义（P<0.05）;治疗3个月后两组患者QT离散度（QTd）、心室除极到完全复极时间（QT间期）、室性早搏频率均降低,且观察组均低于对照组,房室传导时间（PR间期）、室性早搏指数均增加,且观察组均高于对照组,差异有统计学意义（P<0.05）。结论在常规治疗基础上增加麝香保心丸联合β受体阻滞剂治疗可提升冠心病合并室性早搏的治疗效果,可改善患者预后评估过程中心脏超声参数中关于心功能指标水平,降低QT离散度、心室除极到完全复极时间和室性早搏频率,进而改善室性早搏症状。

关键词: 麝香保心丸, β受体阻滞剂, 冠心病, 室性早搏, 心电图, 心功能

Abstract: Objective To explore the combination of Shexiang Baoxin Pills β The application effect of receptor blockers on coronary heart disease with ventricular premature beats and its impact on electrocardiogram indicators. Methods A total of 80 patients with coronary heart disease complicated with ventricular premature beat admitted to Dingxi Hospital of traditional Chinese medicine in Gansu Province from May 2018 to April 2023 were selected for research and analysis. All patients were divided into observation group and control group by lottery, with 40 cases in each group. The control group received routine treatment β Metoprolol, a receptor blocker, was used in the treatment group, and Shexiang Baoxin Pill was added in the observation group on the basis of the control group. The clinical efficacy, cardiac function changes and 24-hour dynamic electrocardiogram monitoring results of the two groups were compared before and after treatment. Results The total effective rate of the observation group was significantly higher than that of the control group (P<0.05); After treatment, the left ventricular ejection fraction (LVEF) of the two groups increased, and the observation group was significantly higher than that of the control group, while the levels of left ventricular end systolic volume (LVESV) and left ventricular end diastolic volume (LVEDV) decreased, and the observation group was lower than that of the control group (P<0.05); After treatment, QT dispersion (QTd), ventricular depolarization to complete repolarization time (QT interval) and ventricular premature beat frequency in the two groups were decreased, and the observation group was lower than the control group, while atrioventricular conduction time (PR interval) and ventricular premature beat index were increased, and the observation group was higher than the control group (P<0.05). Conclusion Combination of Shexiang Baoxin Pill β The therapeutic effect of receptor blockers on coronary heart disease with ventricular premature beats is significant, which can improve the patient's heart function level, improve the patient's electrocardiogram diagnosis results, and improve the symptoms of ventricular premature beats.

Key words: Shexiang Baoxin Pill, β receptor blockers, coronary heart disease, ventricular premature beats, electrocardiogram, cardiac function

中图分类号:

R256.29

杨海龙. 麝香保心丸联合β受体阻滞剂对冠心病合并室性早搏的应用效果及对心电图指标的影响[J]. 中华养生保健, 2024, 42(16): 21-24.

YANG Hai-long. The Effect of Shexiang Baoxin Pill Combined with β-blockers on the Application of Coronary Heart Disease with Premature Ventricular Contractions and the Impact on Electrocardiogram Indicators[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(16): 21-24.

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