早中期微小型甲状腺癌手术治疗的比较研究

摘要/Abstract

摘要： 目的比较早中期微小型甲状腺癌不同手术治疗的效果。方法选择2021年2月—2023年2月在中国贵航集团三〇二医院接受手术治疗的88例微小型甲状腺癌患者作为研究对象,根据手术方式不同将所有患者分为研究组和对照组,每组44例。对照组给予开放甲状腺手术治疗,研究组给予腔镜辅助下的甲状腺手术治疗,比较两组患者血浆甲状腺激素、围手术期指标情况、术后并发症发生情况及疼痛评分变化情况。结果两组术后14 d的血清甲状旁腺激素含量均低于术前1 d,且研究组的血清甲状旁腺激素含量低于对照组,差异有统计学意义（P<0.05）;两组术后14 d血清总三碘甲状腺原氨酸含量均高于术前1 d,且研究组的血清总三碘甲状腺原氨酸含量高于对照组,差异有统计学意义（P<0.05）。两组手术时间比较,差异无统计学意义（P>0.05）。研究组术后带管时间、术后住院时间均短于对照组,术中出血量少于对照组,差异有统计学意义（P<0.05）。研究组术后14 d的低钙血症、声音嘶哑、饮水呛咳、切口感染、喉返神经损伤等并发症发生率低于对照组,差异有统计学意义（P<0.05）。研究组术后1 d、术后7 d、术后14 d的疼痛感VAS评分均低于对照组,差异有统计学意义（P<0.05）。结论早中期微小型甲状腺癌患者采用腔镜辅助下的甲状腺手术治疗,能缩短术后带管时间、术后住院时间,减少术中出血量,还可降低并发症发生率,降低血清甲状旁腺激素含量,提高血清总三碘甲腺原氨酸含量,从而缓解患者的疼痛状况。

关键词: 微小型甲状腺癌, 腔镜, 手术治疗, 甲状旁腺激素, 并发症, 疼痛

Abstract: Objective To compare the effectiveness of different surgical treatments for early to mid stage miniature thyroid cancer. Methods 88 microminiature thyroid cancer patients treated from February 2021 to February 2023 were selected as the research subjects, and all patients were divided into study group and control group according to different surgical methods, with 44 patients in each group.The control group received open thyroid surgery treatment,while the study group received endoscopic assisted thyroid surgery treatment.Recorded the plasma thyroid hormones and perioperative indicators of two groups of patients, as well as the changes in postoperative complications and pain scores. Results At 14 d (P<0.05), the total serum triiodothyronine was higher than 1 d before surgery (P<0.05). At 14 d after surgery, the serum parathyroid hormone and total triiodothyronine content of the study group were significant when compared with the control group (P<0.05). There was not significant (P>0.05).The study group's postoperative tube time, postoperative blood loss and postoperative hospital stay were significantly less than the control group, showing the statistically significant difference (P<0.05). The incidence of hypocalcemia, hoarseness, water cough, incision infection, recurrent laryngeal nerve injury was lower in the control group, with a statistically significant difference (P<0.05). The VAS scores of the study group at 1 d, 7 d and 14 d were lower than that of the control group, which the difference was significant (P<0.05). Conclusion Endoscopic assisted thyroid surgery can reduce postoperative catheterization time, intraoperative bleeding, postoperative hospitalization time, and reduce the incidence of complications in patients with early to mid stage miniature thyroid cancer. It can also reduce serum parathyroid hormone levels, increase serum total triiodothyronine content, and promote pain relief in patients.

Key words: minimal thyroid cancer, endoscopy, surgical treatment, parathyroid hormone, complications, pain

中图分类号:

R736.1

谢磊. 早中期微小型甲状腺癌手术治疗的比较研究[J]. 中华养生保健, 2024, 42(14): 36-39.

XIE Lei. A Comparative Study of Surgical Treatment of Early and Middle Stage Micro Thyroid Cancer[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(14): 36-39.

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