生血宝合剂治疗妊娠期贫血疗效及对RBC、Hb、MCV、FER水平影响

摘要/Abstract

摘要： 目的探讨生血宝合剂治疗妊娠期贫血疗效及对红细胞计数（RBC）、血红蛋白（Hb）、平均红细胞体积（MCV）及血清铁蛋白（FER）水平的影响。方法将2020年5月—2022年8月榆林市横山区人民医院收治的80例妊娠期贫血患者随机分为两组,各40例,对照组予以富马酸亚铁治疗,试验组在对照组基础上予以生血宝合剂治疗。治疗前后检测RBC、Hb、MCV、FER水平,评价临床疗效及安全性,并记录不良围产结局。结果两组治疗后Hb、RBC、MCV、FER水平均明显提高,差异有统计学意义（P<0.05）,试验组FER、Hb、RBC、MCV水平明显高于对照组,差异有统计学意义（P<0.05）。试验组临床疗效明显优于对照组,差异有统计学意义（P<0.05）。两组胎儿发育迟缓、胎儿窘迫、早产、低体质量儿、产褥感染发生率比较,差异无统计学意义（P>0.05）。试验组不良反应发生率明显低于对照组,差异有统计学意义（P<0.05）。结论生血宝合剂辅助治疗妊娠期贫血可提高临床疗效,同时有助于减轻铁剂治疗引起的胃肠道症状,对母婴结局无影响,具有增效减毒的优势。

关键词: 妊娠期贫血, 生血宝合剂, 富马酸亚铁, 贫血指标

Abstract: Objective To investigate the efficacy of Shengxuebao mixture in the treatment of anemia during pregnancy and its effects on red blood cell count (RBC), hemoglobin (Hb), mean red blood cell volume (MCV) and serum ferritin (FER) levels. Methods A total of 80 cases of anemia during pregnancy from May 2020 to August 2022 were randomly divided into two groups, 40 cases in each group. The control group was treated with ferrous fumarate, and the experimental group was treated with Shengxuebao mixture. RBC, Hb, MCV and FER levels were detected before and after treatment to evaluate clinical efficacy and safety, and adverse perinatal outcomes were recorded. Results The levels of Hb, RBC, MCV and FER in the two groups were significantly increased after treatment (P<0.05), and the levels of Hb, RBC, MCV and FER in the experimental group were significantly higher than those in the control group after treatment (P<0.05). The clinical effect of experimental group was significantly better than that of control group (P<0.05). There were no significant difference in the incidence of fetal developmental delay, fetal distress, premature delivery, low birth weight and puerperal infection between the two groups (P>0.05). The incidence of adverse reactions in experimental group was 5.00% and 22.50% in control group, and the incidence of adverse reactions in experimental group was significantly lower than that in control group (P<0.05). Conclusion Shengxuebao mixture can improve clinical efficacy and reduce gastrointestinal symptoms caused by iron treatment,and had no effect on maternal and infant outcomes,. It is safe and effective.

Key words: anemia during pregnancy, shengxue bao mixture, ferrous fumarate, anemia index

中图分类号:

R714.25

赵菊, 薛靓瑀. 生血宝合剂治疗妊娠期贫血疗效及对RBC、Hb、MCV、FER水平影响[J]. 中华养生保健, 2024, 42(13): 25-28.

ZHAO Ju, XUE Liang-yu. Therapeutic Efficacy of Blood-Production Mixture in Treating Anaemia in Pregnancy and Its Effect on RBC, Hb, MCV and FER Levels[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(13): 25-28.

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