通心络胶囊治疗老年冠心病心绞痛疗效分析

摘要/Abstract

摘要： 目的探究分析通心络胶囊用于老年冠心病心绞痛的成效。方法选择2021年5月—2023年5月内蒙古自治区人民医院收治的老年冠心病心绞痛患者100例,依据不同治疗的方式细分为观察组（替米沙坦联合通心络胶囊治疗）、对照组（单用替米沙坦治疗）,各50例。比较分析干预1个月时间患者的心功能指标、生存质量、心绞痛发作情况、硫氧还蛋白互作蛋白（TXNIP）、趋化因子CX3C模体配体1（CX3CL1）指标。结果治疗后,观察组左室射血分数高于对照组,左心室收缩末期内径、左心室舒张末期内径、左心房内径较低,差异有统计学意义（P<0.05）;观察组社会、环境、躯体、心理评分高于对照组,差异有统计学意义（P<0.05）;观察组心绞痛发作频率低于对照组,心绞痛持续时间更短,差异有统计学意义（P<0.05）;观察组CX3CL1、TXNIP指标水平低于对照组,差异有统计学意义（P<0.05）。结论对老年冠心病心绞痛患者联合通心络胶囊干预可提升心功能指标水平和患者的生存质量,缩短心绞痛发作时间,降低发作频率。

关键词: 老年冠心病心绞痛, 通心络, 替米沙坦, 疗效评估, 生存质量

Abstract: Objective To explore and analyze the effectiveness of Tongxinluo capsules in treating elderly patients with coronary heart disease and angina pectoris. Methods From May 2021 to May 2023, 100 elderly patients with coronary heart disease and angina pectoris at the People's Hospital of Inner Mongolia Autonomous Region were selected and divided into an observation group (treated with telmisartan combined with Tongxinluo capsules) based on different treatment methods; The control group (treated with telmisartan alone), with 50 cases each. Comparative analysis of cardiac function indicators, quality of life, incidence of angina pectoris, thioredoxin interaction protein (TXNIP), and chemokine CX3C ligand 1(CX3CL1) indicators in patients undergoing 1-month intervention. Results After treatment, the left ventricular ejection fraction in the observation group was higher than that in the control group, while the left ventricular end systolic diameter, left ventricular end diastolic diameter, and left atrial diameter were lower (P<0.05); The social, environmental, physical, and psychological factors in the observation group were higher than those in the control group (P<0.05); The frequency of angina attacks in the observation group was lower than that in the control group, and the duration of angina was shorter, with a statistically significant difference (P<0.05); The levels of CX3CL1 and TXNIP indicators in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). Conclusion The combination of Tongxinluo Capsule intervention for elderly patients with coronary heart disease and angina pectoris can improve the level of cardiac function indicators and the quality of life of patients, shorten the onset time of angina pectoris, and reduce the frequency of episodes.

Key words: elderly patients with coronary heart disease and angina pectoris, Tongxinluo, telmisartan, efficacy evaluation, quality of life

中图分类号:

R259

刘春婷. 通心络胶囊治疗老年冠心病心绞痛疗效分析[J]. 中华养生保健, 2024, 42(11): 30-33.

LIU Chun-ting. Analysis of the Therapeutic Effect of Tongxinluo Capsule on Elderly Patients with Coronary Heart Disease and Angina Pectoris[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(11): 30-33.

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