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中华养生保健 ›› 2024, Vol. 42 ›› Issue (1): 1-4.

• 论著 •    下一篇

体外反搏联合益心汤对冠心病合并心功能不全气虚血瘀型患者临床疗效观察

赵玉红1, 田君1,*, 宁思思1, 崔兆强2, 颜蕾1, 史嘉炜1, 袁园1   

  1. 1.上海市长宁区天山中医医院内科,上海,200051;
    2.复旦大学附属中山医院心内科,上海,200032
  • 出版日期:2024-01-01 发布日期:2023-12-29
  • 通讯作者: *田君,E-mail: baojun0455@163.com。
  • 作者简介:赵玉红(1970—),女,汉族,籍贯:黑龙江省黑河市,硕士研究生,主任医师,研究方向:心血管内科。
  • 基金资助:
    长宁区卫生健康系统“优质+均衡”科研人才专项资金项目(CN20200610)

Clinical Observation Efficacy of External Counterpulsation Combined with Yixin Decoction in Patients with Coronary Heart Disease Complicated with Cardiac Dysfunction of Qi Deficiency and Blood Stasis

ZHAO Yu-hong1, TIAN Jun1,*, NING Si-si1, CUI Zhao-qiang2, YAN Lei1, SHI Jia-wei1, YUAN Yuan1   

  1. 1. Department of Internal Medicine, Tianshan Hospital of Traditional Chinese Medicine, Changning District, Shanghai 200051, China;
    2. Department of Cardiology, Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • Online:2024-01-01 Published:2023-12-29

摘要: 目的 观察体外反搏联合中药汤剂益心汤对冠心病气虚血瘀型合并心功能不全患者的临床疗效。方法 选取2021年1月—2022年1月长宁区天山中医医院收治的50例冠心病气虚血瘀型合并心功能不全患者患者为研究对象,按照随机数表法分为观察组(25例,体外反搏+益心汤+常规药物治疗)和对照组(25例,益心汤+常规药物治疗),观察两组患者治疗前后中医证候评分、6 min步行试验距离、心脏功能、血清脑钠肽(BNP)等变化。结果 治疗后,两组中医证候评分、血清BNP水平均降低,心脏射血分数、6 min步行距离均增加,差异有统计学意义(P<0.05);治疗后,观察组患者胸闷憋气、心悸症状评分较对照组低,6 min步行距离及心脏射血分数较对照组高,差异有统计学意义(P<0.05)。结论 体外反搏联合中药汤剂益心汤及常规西药治疗,较单纯西药治疗方案对气虚血瘀型冠心病合并心功能不全患者的6 min步行距离、BNP、心脏射血分数有正向治疗作用,同时可改善中医临床证候,使患者在生活质量上获益更大。

关键词: 体外反搏, 益心汤, 冠心病, 气虚血瘀, 心功能不全

Abstract: Objective To observe the clinical effect of external counterpulsation combined with traditional Chinese medicine decoction Yixin Decoction on coronary heart disease patients with qi deficiency and blood stasis type combined with cardiac insufficiency. Methods Selected 50 patients who met the inclusion criteria from January 2021 to January 2022 in the Department of Cardiovascular Medicine, Tianshan Hospital of Traditional Chinese Medicine, Changning District. They were randomly divided into an observation group (25 cases, receiving external counterpulsation + Yixin Decoction + conventional drug treatment) and a control group (25 cases, receiving Yixin Decoction + conventional drug treatment), The TCM symptom scores, cardiac function, 6-minute walking distance (6MWD), serum brain natriuretic peptide (BNP) and other changes were observed before and after treatment in the two groups of patients. Results Patients in the observation and control groups had lower TCM evidence scores and serum BNP after treatment, cardiac ejection fraction and 6-minute walking distance were higher than those before treatment (P<0.05). After treatment, the symptom scores of chest tightness and palpitation in observation group were reduced compared with control group, and the 6-minute walking distance,cardiac ejection fraction were improved compared with control group (P<0.05). Conclusion The combination of external counterpulsation with traditional Chinese medicine decoction Yixin Tang and conventional Western medicine treatment has a positive therapeutic effect on the six minute walking distance, BNP, and LVEF of patients with Qi deficiency and blood stasis type coronary heart disease combined with cardiac insufficiency compared to a simple Western medicine treatment plan. At the same time, it improves the clinical syndrome score of traditional Chinese medicine and benefits patients more in terms of quality of life.

Key words: external counterpulsation, Yixin decoction, coronary heart disease, qi deficiency and blood stasis, cardiac insufficiency

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