黄芪桂枝五物汤外洗法对化疗后末梢神经炎治疗效果评价

摘要/Abstract

摘要： 目的分析黄芪桂枝五物汤外洗法治疗化疗后末梢神经炎的疗效。方法选取2021年1月—2022年5月黑龙江省医院收治的60例化疗后末梢神经炎患者为研究对象,按随机数表法将其分入中药外洗组（30例）和对照组（30例）,对照组患者给予常规治疗及维生素治疗,中药外洗组患者在对照组的基础上加用黄芪桂枝五物汤外洗法治疗。比较两组患者总体疗效和治疗前后视觉模拟评分法（VAS）评分、血清白细胞介素-1β（IL-1β）、肿瘤坏死因子-α(TNF-α)水平改善情况。结果中药外洗组患者总有效率均显著高于对照组（P<0.05）。两组患者治疗前血清IL-1β、TNF-α水平和疼痛评分比较,差异无统计学意义（P>0.05）;干预后,两组血清IL-1β、TNF-α水平和疼痛评分均较干预前明显下降,且中药外洗组患者血清IL-1β、TNF-α水平和疼痛评分均显著低于对照组（P<0.05）。结论黄芪桂枝五物汤外洗法治疗化疗后末梢神经炎具有良好的疗效,能有效改善机体炎症状况,降低疼痛程度,提高患者的总体治疗效果,是一种安全高效的治疗方式。

关键词: 黄芪桂枝五物汤, 外洗, 化疗, 末梢神经炎, 疗效

Abstract: Objective To analyze the efficacy of Huangqi Guizhi Wuwu Decoction in the treatment of peripheral neuritis after chemotherapy. Methods From January 2021 to May 2022, 60 patients with peripheral neuritis after chemotherapy who were treated in Heilongjiang Provincial Hospital were selected as the study subjects. They were randomly divided into two groups according to the digital grouping method: the external washing group with traditional Chinese medicine (30 cases) and the control group (30 cases). The control group patients were given routine treatment and vitamin treatment, and the external washing group patients were treated with Huangqi Guizhi Wuwu Decoction on the basis of the control group. Compare the overall efficacy, visual analog scale (VAS), and serum interleukin-1 of the two groups of patients before and after treatment β (IL-1β), Tumor necrosis factor-α(TNF-α) Level improvement. Results The total effective rate of patients in the external washing group was significantly higher than that in the control group (P<0.05). Before treatment, there was no significant difference in serum IL-1β, TNF-α levels and pain scores between the two groups (P>0.05). After intervention, serum IL-1β、 TNF-α and pain scores were significantly decreased (P<0.05), with a significant difference compared to before intervention (P<0.05), and the serum IL-1β, TNF-α of patients in the external washing group of traditional Chinese medicine was also significantly decreased (P<0.05). The decrease in pain scores was significantly greater in the control group than in the control group (P<0.05). Conclusion Huangqi Guizhi Wuwu Decoction has a good therapeutic effect on peripheral neuritis after chemotherapy, which can effectively improve the inflammatory status of the body, reduce the degree of pain, and improve the overall treatment effect of patients. It is a safe and efficient treatment method.

Key words: Huangqi Guizhi Wuwu Decoction, external washing, chemotherapy, peripheral neuritis, curative effect

中图分类号:

R269

马国章, 李晓林, 李南南, 刘志鹏, 姜海微. 黄芪桂枝五物汤外洗法对化疗后末梢神经炎治疗效果评价[J]. 中华养生保健, 2023, 41(19): 22-25.

MA Guo-zhang, LI Xiao-lin, LI Nan-nan, LIU Zhi-peng, JIANG Hai-wei. Evaluation of the Therapeutic Effect of Huangqi Guizhi Wuwu Decoction on Peripheral Neuritis after Chemotherapy[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(19): 22-25.

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