易黄汤加味联合穴位贴敷对HPV阳性慢性宫颈炎患者HPV转阴及炎症反应的影响

中华养生保健 ›› 2023, Vol. 41 ›› Issue (17): 32-35.

易黄汤加味联合穴位贴敷对HPV阳性慢性宫颈炎患者HPV转阴及炎症反应的影响

郭伟¹, 杨艳², 王英^2,*

1.日照市东港区妇幼保健院中医科,山东日照,276800;
2.日照市东港区妇幼保健院妇科,山东日照,276800

出版日期:2023-09-01 发布日期:2023-08-30
通讯作者: ^*杨艳,E-mail：guowei8822@163.com。
作者简介:郭伟（1980—）,男,汉族,籍贯：山东省日照市,本科,副主任医师,研究方向：中医妇科。

Effect of Modified Yihuang Decoction Combined with Acupoint Application on HPV Negative Transformation and Inflammatory Reaction in Patients with HPV Positive Chronic Cervicitis

GUO Wei¹, YANG Yan², WANG Ying^2,*

1. Traditional Chinese medicine Donggang District Maternal and Child Health Care of Rizhao, Rizhao Shandong 276800, China;
2. Gynecology Department, Traditional Chinese medicineDonggang District Maternal and Child Health Care of Rizhao, Rizhao Shandong 276800, China

Online:2023-09-01 Published:2023-08-30

摘要/Abstract

摘要： 目的探讨易黄汤加味联合穴位贴敷在人乳头瘤病毒（HPV）阳性慢性宫颈炎（CCS）患者中的应用价值。方法回顾性分析2021年9月—2022年9月日照市东港区妇幼保健院收治的74例HPV阳性CCS患者的临床资料,按治疗方式不同进行分组,其中行常规治疗的37例患者为对照组,行易黄汤加味联合穴位贴敷治疗的37例患者为观察组,两组均治疗4周。对比分析两组HPV转阴情况、炎症反应、免疫功能、中医证候积分、不良反应。结果观察组HPV转阴率高于对照组,差异有统计学意义（P<0.05）;治疗后,观察组超敏C反应蛋白（hs-CRP）、白介素（IL）-10、IL-6、IL-2、肿瘤坏死因子-α（TNF-α）水平及带下量多评分、带下颜色异常评分、腰酸坠胀评分、口苦咽干评分、小便频数疼痛评分低于对照组,CD4⁺、CD8⁺、CD4⁺/CD8⁺高于对照组,差异有统计学意义（P<0.05）;两组均未出现不良反应。结论易黄汤加味联合穴位贴敷能够促使HPV阳性CCS患者HPV转阴,减轻炎症反应,提高机体免疫力,加快疾病恢复,且安全性较高。

关键词: 慢性宫颈炎, 人乳头瘤病毒, 易黄汤加味, 穴位贴敷, 炎症反应, 免疫功能

Abstract: Objective To explore the application value of modified Yihuang Decoction combined with acupoint application in patients with HPV positive chronic cervicitis (CCS). Methods The clinical data of 74 patients with HPV-positive CCS admitted to Donggang District Maternal and Child Health Hospital of Rizhao City from September 2021 to September 2022 were analyzed retrospectively. They were divided into groups according to different treatment methods, among which 37 patients who received routine treatment were the control group, and 37 patients who received modified Yihuang Decoction combined acupoint application treatment were the observation group. Both groups were treated for 4 weeks. Compare and analyze the negative conversion of HPV, inflammatory reaction, immune function, TCM syndrome score and adverse reactions between the two groups. Results The negative rate of HPV in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05), After treatment, in the observation group, hypersensitive C-reactive protein (hs-CRP), interleukin (IL)-10, IL-6, IL-2, tumor necrosis factor-α(TNF-α) and the scores of excessive underband volume, abnormal underband color, low back pain and bloating, bitter mouth and dry throat, and frequent urination pain were lower than those of the control group, and the scores of CD4⁺, CD8⁺, CD4⁺/CD8⁺were higher than those of the control group, with statistically significant differences (P<0.05); There were no adverse reactions in both groups. Conclusion Modified Yihuang Decoction combined with acupoint application can promote HPV negative in HPV-positive CCS patients, reduce inflammatory reaction, improve immunity, and accelerate symptom recovery, with high safety.

Key words: chronic cervicitis, human papillomavirus, modified Yihuang Decoction, acupoint application, inflammatory response, immune function

中图分类号:

R711

郭伟, 杨艳, 王英. 易黄汤加味联合穴位贴敷对HPV阳性慢性宫颈炎患者HPV转阴及炎症反应的影响[J]. 中华养生保健, 2023, 41(17): 32-35.

GUO Wei, YANG Yan, WANG Ying. Effect of Modified Yihuang Decoction Combined with Acupoint Application on HPV Negative Transformation and Inflammatory Reaction in Patients with HPV Positive Chronic Cervicitis[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(17): 32-35.

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