鲁北地区女性不孕症患者宫腔镜结果分析

摘要/Abstract

摘要： 目的分析2 123例鲁北地区女性不孕症患者宫腔镜检查结果。方法回顾性分析2015年1月—2021年12月在滨州医学院附属医院行宫腔镜检查的2 123例[不孕症1 426例、不良妊娠史448例、宫内受精（IUI）助孕失败史61例、体外受精联合胚胎移植技术（IVF）助孕失败史188例]鲁北地区女性不孕患者的病历资料,比较不同不孕类型、年龄段、不良妊娠次数、IUI/IVF助孕失败次数患者的宫腔镜检查结果。结果因不孕症行宫腔镜检查的患者有1 426例,结果异常686例,异常率48.11%。原发不孕428例（原发不孕组）,结果异常240例,异常率56.07%;继发不孕998例（继发不孕组）,结果异常446例,异常率44.69%。原发不孕组子宫内膜息肉发病率、慢性子宫内膜炎发病率、子宫发育异常发病率均高于继发不孕组（P<0.05）。继发不孕组宫腔粘连发病率高于原发不孕组（P<0.05）。随着年龄增长,总体异常率呈下降趋势（P>0.05）,子宫发育异常率逐渐降低（P<0.05）。随着不孕年限增加,总体异常率逐渐升高（P<0.05）。随着不良妊娠次数增加,宫腔镜异常率逐渐增加（P<0.05）。随着IUI助孕失败次数增加,宫腔镜异常率呈增加趋势（P>0.05）。随着移植失败次数增加,宫腔镜异常率呈下降趋势（P>0.05）。结论鲁北地区女性不孕症患者宫腔异常率较高,宫腔镜总体异常率与不孕因素有关,子宫发育异常率与年龄有关。对于不孕年限≥3年、不良妊娠次数≥3次者,建议完善宫腔镜检查。

关键词: 宫腔镜检查, 不孕症, 子宫内膜息肉, 慢性子宫内膜炎, 宫腔粘连, 子宫发育异常

Abstract: Objective To analysis the hysteroscopy results of 2 123 female infertility patients in northern Shandong. Methods Retrospective analysis was performed on the case data of 2 123 female infertility patients in northern Shandong who underwent hysteroscopy in the Department of Reproductive Medicine of our hospital from January 2015 to December 2021 due to infertility (1 426 cases), adverse pregnancy history (448 cases), history of pregnancy failure assisted by IUI (61 cases) and history of pregnancy failure assisted by IVF (188 cases). The hysteroscopy results of patients with different types of infertility, age group, number of adverse pregnancies, and number of failed pregnancies assisted by IUI/IVF were compared. Results Among 1426 patients undergoing hysteroscopy due to infertility, 686 had abnormal results, with an abnormal rate of 48.11%. There were 428 cases of primary infertility, and 240 cases were abnormal, with an abnormal rate of 56.07%. There were 998 cases of secondary infertility, and 446 cases were abnormal, the abnormal rate was 44.69% (P<0.05). The incidence of endometrial polyp, chronic endometritis and abnormal uterine development in primary infertility group was 21.73%, 21.73% and 3.97%, respectively, which were higher than those in secondary infertility group (P<0.05). The incidence of intrauterine adhesions in secondary infertility group was 9.92% higher than that in primary infertility group (P<0.05). With the increase of age, the overall abnormal rate showed a downward trend (P>0.05), and the abnormal rate of uterine development gradually decreased (P<0.05). With the increase of infertility years, the overall abnormal rate gradually increased (P<0.05). The abnormal rate of hysteroscopy increased gradually with the increase of the number of adverse pregnancies (P<0.05). With the increase of IUI-assisted pregnancy failure, hysteroscopy abnormality rate showed an increasing trend (P>0.05). The abnormal rate of hysteroscopy decreased with the increase of transplant failure (P>0.05). Conclusion The uterine abnormality rate of female infertility patients in northern Shandong is high, the overall abnormal rate of hysteroscopy is related to infertility factors, and the abnormal rate of uterine development is related to age. The duration of infertility is greater than or equal to 3 years, and the number of adverse pregnancies is greater than or equal to 3 times. Hysteroscopy is recommended.

Key words: hysteroscopy, infertility, endometrial polyps, chronic endometrial, intrauterine adhesion, uterine malformation

中图分类号:

R713.7

庞益伟, 尹红梅, 王新花, 丁艳霞, 韩磊. 鲁北地区女性不孕症患者宫腔镜结果分析[J]. 中华养生保健, 2023, 41(11): 10-13.

PANG Yi-wei, YIN Hong-mei, WANG Xin-hua, DING Yan-xia, HAN Lei. Clinical Analysis of Hysteroscopy Results of Infertile Patients in Northern Shandong[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(11): 10-13.

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