荧光支气管镜对锁骨上淋巴结转移的非小细胞肺癌患者的诊断价值

摘要/Abstract

摘要： 目的探讨荧光支气管镜检查对锁骨上淋巴结转移的非小细胞肺癌患者的诊断价值。方法选择2019年5月~2022年1月在江苏省淮安市第五人民医院诊治的非小细胞肺癌患者80例,所有患者都给予白光与荧光支气管镜检查,同时给予手术病理检查,以病理检查为金标准,判断荧光支气管镜的诊断价值。结果在80例患者中,手术病理确诊为锁骨上转移淋巴结16例（转移组）,占比20.00%。转移组的性别、年龄、体质量指数、病理类型等与非转移组对比,差异无统计学意义（P>0.05）。白光支气管镜与荧光支气管镜检查诊断非小细胞肺癌患者锁骨上转移淋巴结的敏感度分别为93.75%（15/16）和100.00%（16/16）,特异度分别为85.94%（55/64）和98.44%（63/64）,准确度分别为87.50%（70/80）和98.75%（79/80）。荧光支气管镜检查诊断非小细胞肺癌患者锁骨上转移淋巴结的特异度明显高于白光支气管镜检查,差异有统计学意义（P<0.05）;不同检查方法的敏感度对比,差异无统计学意义（P>0.05）。结论荧光支气管镜检查对锁骨上淋巴结转移的非小细胞肺癌患者的诊断可在保持高灵敏度的基础上提高诊断的特异度、准确度,具有很好的诊断效果。

关键词: 白光支气管镜, 荧光支气管镜, 非小细胞肺癌, 锁骨上转移淋巴结

Abstract: Objective To explore the diagnostic value of fluorescence bronchoscopy in patients with non-small cell lung cancer with supraclavicular lymph node metastasis. Methods From May 2019 to January 2022, A total of 80 cases of patients with non-small cell lung cancer who were diagnosed and treated in our hospital were selected as the research subjects. All patients were given white light and fluorescence bronchoscopy, as well as surgical and pathological examinations, with pathological examination as gold standard to judge the diagnostic value. Results In the 80 patients, there were 16 cases (metastasis group) diagnosed as supraclavicular metastatic lymph nodes by surgery and pathology, accounted for 20.00%. There was no significant difference in gender, age, body mass index and pathological type compared between the metastatic group and the non-metastatic group (P>0.05). The sensitivity of white light bronchoscopy and fluorescence bronchoscopy in the diagnosis of supraclavicular lymph nodes in patients with non-small cell lung cancer was 93.75% (15/16) and 100.00% (16/16), respectively, and the specificity were 85.94% (55/64) and 98.44% (63/64), and the accuracy were 87.50% (70/80) and 98.75% (79/80). The specificity of fluorescence bronchoscopy in diagnosing supraclavicular lymph nodes in patients with non-small cell lung cancer was significantly higher than that of white light bronchoscopy (P<0.05). There was no significant difference in sensitivity between different methods (P>0.05). Conclusion Fluorescence bronchoscopy in the diagnosis of non-small cell lung cancer patients with supraclavicular lymph node metastasis can improve the specificity, accuracy of diagnosis on the basis of maintaining high sensitivity, and has a good diagnostic effect.

Key words: white light bronchoscopy, fluorescence bronchoscopy, non-small cell lung cancer, supraclavicular metastatic lymph nodes

中图分类号:

R768.1

黄长明. 荧光支气管镜对锁骨上淋巴结转移的非小细胞肺癌患者的诊断价值[J]. 中华养生保健, 2022, 40(22): 15-17.

HUANG Chang-ming. The Diagnostic Value of Fluorescence Bronchoscopy in Patients with Non-Small Cell Lung Cancer with Supraclavicular Lymph Node Metastasis[J]. ZHONGHUA YANGSHENG BAOJIAN, 2022, 40(22): 15-17.

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