2型糖尿病患者发生颈动脉粥样硬化的危险因素

摘要/Abstract

摘要： 目的探究2型糖尿病患者发生颈动脉粥样硬化的危险因素。方法选取内蒙古自治区人民医院2019年1月~2021年12月收治的125例2型糖尿病患者作为研究对象。对比两组患者的临床资料,分析2型糖尿病患者发生颈动脉粥样硬化的危险因素。结果 125例2型糖尿病患者中发生颈动脉粥样硬化的患者有68例,发生率为54.40%;通过单因素分析,年龄、BMI、吸烟史、高血压史、糖尿病病程、高密度脂蛋白胆固醇（HDL-C）、胰岛素规律治疗、甘油三酯（TG）、糖化血红蛋白（HbA_1c）与2型糖尿病动脉粥样硬化的发生有关（P<0.05）,而在饮酒史、胰岛素规律治疗、舒张压（DBP）、空腹血糖（FBG）、收缩压（SBP）、餐后2 h血糖（2 h PBG）、总胆固醇（TC）、空腹胰岛素方面比较,差异无统计学意义（P>0.05）;经二元Logistic回归分析,以2型糖尿病患者有无动脉粥样硬化作为因变量（非硬化组=0,硬化组=1）,以年龄、BMI、吸烟史、高血压史、糖尿病病程、HDL-C、胰岛素规律治疗、TG、HbA_1c为自变量,经二元Logistic回归分析结果显示,年龄、HDL-C、高血压史、糖尿病病程、胰岛素规律治疗、TG、HbA_1c为2型糖尿病患者发生动脉粥样硬化的危险因素。结论年龄、糖尿病病程、高血压史、HDL-C、胰岛素规律治疗、TG、HbA_{1 c}是2型糖尿病患者发生颈动脉粥样硬化的危险因素,预防上述因素可延缓患者颈动脉粥样硬化的发生。

关键词: 2型糖尿病患者, 颈动脉粥样硬化, 危险因素

Abstract: Objective To explore the risk factors of carotid atherosclerosis in patients with type 2 diabetes. Methods A total of 125 patients with type 2 diabetes who visited the People's Hospital of Inner Mongolia Autonomous Region from January 2019 to December 2021 were selected as the research subjects. The clinical data of the two groups of patients were compared, and the risk factors of carotid atherosclerosis in patients with type 2 diabetes were analyzed. Results Among the 125 patients with type 2 diabetes, 68 patients had carotid atherosclerosis, and the incidence rate was 54.40%. The results of univariate analysis were: age, BMI, smoking history, hypertension history, diabetes duration, high density liptein cholesterol (HDL-C), regular insulin therapy, triglyceride (TG), glycosylated hemoglobin (HbA_1c) were associated with the occurrence of atherosclerosis in type 2 diabetes (P<0.05), while drinking history, regular insulin therapy, diastolic blood pressure (DBP), fasting There was no statistically difference in blood glucose (FBG), systolic blood pressure (SBP), 2 h postprandial blood glucose (2 h PBG),total cholesterol (TC) and fasting insulin (P>0.05); binary logistic regression analysis , taking the presence or absence of atherosclerosis in patients with type 2 diabetes as the dependent variable (non-sclerosis group=0, sclerosis group=1), age, BMI, smoking history, history of hypertension, duration of diabetes, HDL-C, insulin regular treatment , TG, and HbA_{1 c} are independent variables. Binary Logistic regression analysis shows that age, HDL-C, history of hypertension, diabetes duration, regular insulin therapy, TG, and HbA_{1 c} are risk factors for atherosclerosis in patients with type 2 diabetes. Conclusion Age, duration of diabetes, history of hypertension, HDL-C, regular insulin therapy, TG and HbA_{1 c} are risk factors for carotid atherosclerosis in type 2 diabetes. Preventing the above factors can delay the occurrence of carotid atherosclerosis in patients.

Key words: Type 2 diabetes mellitus, carotid atherosclerosis, risk factors

中图分类号:

杨贞, 赵杰. 2型糖尿病患者发生颈动脉粥样硬化的危险因素[J]. 中华养生保健, 2022, 40(15): 8-11.

YANG Zhen,ZHAO Jie. Risk Factors for Carotid Atherosclerosis in Patients with Type 2 Diabetes[J]. ZHONGHUA YANGSHENG BAOJIAN, 2022, 40(15): 8-11.

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