金丹排石汤治疗湿热型输尿管结石的临床效果

摘要/Abstract

摘要： 目的探讨金丹排石汤治疗湿热型输尿管结石的临床效果。方法选取2021年1月—2022年12月在平邑县人民医院住院的湿热型输尿管结石患者62例,按随机数表法分为治疗组与对照组,每组31例。治疗组给予金丹排石汤治疗,对照组给予肾石通颗粒,连续30 d。根据WHO疼痛等级评价患者的疼痛程度,记录患者的中医证候评分、排尿次数、尿量;生化法检测尿白细胞和红细胞数量、血白细胞分类和数量、肌酐和尿素氮水平;影像学检查输尿管结石的大小和数量;最后综合评价两组患者的总有效率。结果治疗后两组患者的临床疼痛等级和疼痛时间、舌苔颜色和脉象、尿量和排尿次数均显著改善,结石大小和数量均显著减少,尿白细胞和红细胞计数显著减少,血肌酐和尿素氮水平显著下降,血白细胞计数显著降低,差异有统计学意义（P<0.05）。治疗后治疗组患者的临床疼痛等级和时间较对照组显著降低,差异具有统计学意义（P<0.05）;尿白细胞数量、尿红细胞数量、血肌酐和尿素氮水平、血白细胞计数均显著低于对照组,差异具有统计学意义（P<0.05）。治疗组患者的总有效率显著高于对照组,差异具有统计学意义（P<0.05）。结论金丹排石汤可改善输尿管结石患者的临床症状和肾功能,增强白细胞的抗炎作用。

关键词: 金丹排石汤, 输尿管结石, 湿热证, 临床疗效

Abstract: Objective This study aims to explore the clinical efficiency of Jindan Paishi (JDPS) decoction in treating patients with damp-heat type of ureteral calculus. Methods Total of 62 patients of ureteral calculus with damp -heat syndrome were hospitalized in Peoples' Hospital of Pingyi County from Jan 2021 to Dec 2022. According to randomized digital table method, all patients were randomly divided into treatment group (n=31) orally treated with JDPS decoction and control group (n=31) orally given Shenshitong granules for 30 days continuously. The pain degrees of patients were evaluated according to WHO Pain Grade. The traditional Chinese medicine (TCM) syndromes, micturition frequency and urine volume were recorded. The number of WBC and RBC in urine, the WBC classification and numbers in blood, creatinine and urea nitrogen were determined by biochemical assay. The size and number of ureteral calculus were detected by imaging examination, and at last the total effective rate of the two drugs was evaluated comprehensively. Results After treatment, all the pain degree and pain time, the tongue coating color and pulse conditions, the size and number of ureteral calculus, the urine volume and times of patients were significantly improve than those before treatment respectively; the size and number of ureteral calculus were significantly reduced than those before treatment; the numbers of WBC and RBC in urine were significantly decreased than those before treatment; the creatinine (Cr) and urea nitrogen (BUN) levels in serum were significantly decreased than those before treatment; the numbers of blood WBC was significantly reduced while the neutrophils and lymphocytes increased than those before treatment(P<0.05). The pain degree and time of patients in treatment group were significantly decreased than those in control group(P<0.05); the number of WBC in urine,the number of RBC,the serum levels of Cr and BUN, and the number of WBC in blood in treatment group were significantly lower than those in control group(P<0.05). The total effective rate of patients in treatment group (90.32%) was significantly higher than that in control group (80.64%)(P<0.05). Conclusion sJDPS decoction might improve clinical symptoms and renal function of patients with damp-heat type of ureteral calculus, and enhance the anti-inflammatory effect of blood WBC.

Key words: Jindan Paishi decoction, ureteral calculus, damp-heat syndrome, clinical effect

中图分类号:

R277.5

孙涛, 蔡珂, 刘姿杉, 周春丽, 孙龙军. 金丹排石汤治疗湿热型输尿管结石的临床效果[J]. 中华养生保健, 2024, 42(9): 12-16.

SUN Tao, CAI Ke, LIU Zi-shan, ZOU Chun-li, SIN Long-jun. The Clinical Efficiency of Jindan Paishi Decoction in Treating Patients with Damp-Heat Type of Ureteral Calculus[J]. ZHONGHUA YANGSHENG BAOJIAN, 2024, 42(9): 12-16.

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