右美托咪定和丙泊酚对蛛网膜下腔麻醉老年髋关节置换术中脑氧饱和度的影响

摘要/Abstract

摘要： 目的评价蛛网膜下腔麻醉后老年髋关节置换术患者脑氧饱和度（rSO₂）的变化,并比较右美托咪定和丙泊酚镇静后脑氧饱和度和血氧饱和度的变化。方法选取内蒙古自治区人民医院210例ASAⅡ~Ⅲ级、既往无脑部疾病史、无严重心血管或呼吸系统疾病、行髋关节置换的患者,蛛网膜下腔麻醉后,按随机数表法分为右美托咪定组和丙泊酚组,每组105例。麻醉后对平均动脉压（MAP）、心率（HR）、脑氧饱和度（rSO₂）、经皮血氧饱和度（SPO₂）、脑电双频指数（BIS）进行测量。蛛网膜下腔麻醉后20 min,开始使用右美托咪定或丙泊酚镇静。在使用右美托咪定或丙泊酚的10 min、30 min、60 min测量各项数据。结果蛛网膜下腔麻醉对rSO₂无显著影响，给予右美托咪定或丙泊酚后两组患者rSO₂无统计学差异，但是右美托咪定组的MAP和SPO2明显高于丙泊酚组。结论在蛛网膜下腔麻醉时使用右美托咪定或丙泊酚进行镇静并不影响脑氧饱和度。在右美托咪定镇静中，MAP和SpO₂比在丙泊酚镇静中更稳定。因此，右美托咪定可能更适合用于椎管内麻醉的短期镇静。

关键词: 右美托咪定, 丙泊酚, 蛛网膜下腔麻醉, 脑氧饱和度, 经皮血氧饱和度

中图分类号:

R614

郝伟, 范惟, 王佳妮, 王超, 贾艳. 右美托咪定和丙泊酚对蛛网膜下腔麻醉老年髋关节置换术中脑氧饱和度的影响[J]. 中华养生保健, 2024, 42(8): 187-192.

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