纤维支气管镜在儿童重症支原体肺炎治疗中的运用

摘要/Abstract

摘要： 目的探讨纤维支气管镜在儿童重症支原体肺炎治疗中的作用。方法选取2021年1月—2022年1月聊城市第二人民医院收治的50例重症支原体肺炎患儿为研究对象,随机分为两组,对照组施以阿奇霉素、甲泼尼龙琥珀酸钠等常规抗感染药物方案,试验组同时施以纤维支气管镜肺泡灌洗方案。比较两组患儿治疗效果、症状改善时间、住院时间、炎症指标、并发症发生情况。结果试验组患儿的总有效率高于对照组,但差异无统计学意义（P>0.05）。试验组体温恢复时间、啰音消失时间、咳嗽消失时间及住院时间均短于对照组,差异有统计学意义（P<0.05）。两组治疗后C-反应蛋白（CRP）、红细胞沉降率（ESR）、降钙素原（PCT）水平均较治疗前更低,差异有统计学意义（P<0.05）;试验组治疗后CRP、ESR、PCT水平均低于对照组,差异有统计学意义（P<0.05）。两组并发症发生率比较,差异无统计学意义（P>0.05）。结论针对儿童重症支原体肺炎予以纤维支气管镜治疗,与常规抗感染方案相比,能获取较好的效果,可进一步缩短住院的时间,促进患儿炎症因子指标的改善,且纤维支气管镜术治疗无明显不良事情发生。

关键词: 纤维支气管镜, 儿童, 重症支原体肺炎, 降钙素原

Abstract: Objective To evaluate the efficacy of fiberoptic bronchoscopy in alleviating severe mycoplasma pneumonia in children. Method A total of 50 children with severe mycoplasma pneumonia who were hospitalized in Liaocheng Second People's Hospital from January 2021 to January 2022 were selected as the research objects, and they were randomized divided into two groups. The control group was given azithromycin and methylprednisolone succinate. Sodium and other conventional anti-infective drug regimens were given, and the experimental group was also given a bronchoalveolar lavage regimen with fiberoptic bronchoscopy. The differences in the treatment effect, symptom improvement time, hospital stay, inflammatory indexes and complications were compared between the two groups. Results The total effective rate of children with severe mycoplasma pneumoniae pneumonia in experimental group was higher than that in control group, but the difference was not statistically significant (P>0.05). Temperature recovery time index, rales disappearance time index, cough disappearance time index and hospital stay index in the experimental group were lower than in the control group (P<0.05). The levels of C-reactive protein (CRP), erythrocyte sedimentation rate and procalcitonin (PCT) in the two groups after treatment were lower than those before treatment (P<0.05). The levels of CRP, erythrocyte sedimentation rate and PCT in the experimental group were lower than those in the control group (P<0.05). There was no significant difference in complication rate between the two groups (P>0.05). Conclusion Compared with the conventional anti-infection regimen, fiberoptic bronchoscopy can achieve better results in the treatment of severe mycoplasma pneumonia in children. It can further shorten the hospitalization time, promote the improvement of inflammatory factors in children, and fiberoptic bronchoscopy treatment has no obvious adverse events.

Key words: fiberoptic bronchoscope, children, severe mycoplasma pneumonia, erythrocyte sedimentation rate, procalcitonin

中图分类号:

R563.1

杨丽昆. 纤维支气管镜在儿童重症支原体肺炎治疗中的运用[J]. 中华养生保健, 2023, 41(5): 11-14.

YANG Li-kun. Application of Fiberoptic Bronchoscope in the Treatment of Severe Mycoplasma Pneumonia in Children[J]. ZHONGHUA YANGSHENG BAOJIAN, 2023, 41(5): 11-14.

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