气道廓清技术联合痰热清注射液对脑卒中相关性肺炎气管切开患者的影响

中华养生保健 ›› 2022, Vol. 40 ›› Issue (23): 161-164.

气道廓清技术联合痰热清注射液对脑卒中相关性肺炎气管切开患者的影响

罗辉¹, 吴颖¹, 仝霖¹, 谭华桥², 陈成^3,*

1.上海市普陀区利群医院急诊医学科,上海,200333;
2.上海市同济大学附属同济医院神经介入科,上海,200065;
3.苏州大学附属第一医院呼吸与危重症医学科,江苏苏州,215006

出版日期:2022-12-01 发布日期:2022-11-24
通讯作者: ^*陈成,E-mail：chencheng@suda.edu.cn。
作者简介:罗辉（1981.11-）,男,汉族,籍贯：四川省南充市,本科,主治医师,研究方向：急性缺血性卒中,卒中相关肺炎。

Effect of Airway Clearance Technique combined with Tanreqing Injection on Patients with Stroke associated Pneumonia undergoing Tracheotomy

LUO Hui¹, WU Ying¹, TONG Lin¹, TAN Hua-qiao², CHEN Cheng^3,*

1. Department of Emergency Medicine, Liqun Hospital, Putuo District, Shanghai, 200333, China;
2. Department of Neurointervention, Tongji Hospital Affiliated to Tongji University, Shanghai, 200065, China;
3. Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215006, China

Online:2022-12-01 Published:2022-11-24

摘要/Abstract

摘要： 目的探讨气道廓清技术联合痰热清注射液对脑卒中相关性肺炎气管切开患者的影响。方法选取2019年2月~2022年2月在上海市普陀区利群医院和上海市同济大学附属同济医院就诊的脑卒中相关性肺炎气管切开患者80例,依据随机数表法分为观察组（气道廓清技术+痰热清注射液）和对照组（气道廓清技术）,各40例。对比两组临床疗效,美国国立卫生研究院卒中量表（NIHSS）评分和临床肺部感染评分（CPIS）评分,治疗前后血降钙素原（PCT）和全血白细胞计数（WBC）水平,以及拔管时间、拔管成功率和抗生素使用时间。结果观察组总有效率显著高于对照组（P<0.05）。观察组NIHSS评分和CPIS评分均显著低于对照组（P<0.05）。治疗后两组PCT和WBC水平均显著低于治疗前（P<0.05）,且观察组PCT和WBC水平均显著低于对照组（P<0.05）。观察组拔管时间、拔管成功率和抗生素使用时间均显著短于对照组（P<0.05）。结论气道廓清技术联合痰热清注射液治疗脑卒中相关性肺炎气管切开患者效果显著,可有效改善患者神经功能,控制肺感染,降低血清炎症因子水平,缩短拔管时间,提高拔管成功率。

关键词: 脑卒中, 肺炎, 气管切开, 气道廓清技术, 痰热清注射液

Abstract: Objective To investigate the effect of airway clearance technique combined with Tanreqing Injection on patients with stroke associated pneumonia undergoing tracheotomy. Methods A total of 80 patients with stroke-related pneumonia who underwent tracheotomy in Liqun Hospital of Putuo District, Shanghai and Tongji Hospital Affiliated to Tongji University, Shanghai from February 2019 to February 2022 were selected and randomly divided into observation group (gas Dao clearing technique + Tanreqing injection) and control group (airway clearing technique) with 40 cases each. The clinical efficacy, National Institutes of Health Stroke Scale (NIHSS) score and Clinical Pulmonary Infection Score (CPIS), procalcitonin (PCT) and white blood cell count (WBC) levels before and after treatment, and extubation time, extubation success rate and antibiotic use time were compared between the two groups. Results The total effective rate of the observation group, was significantly higher than the control group (P<0.05). The NIHSS score and CPIS score in the observation group were significantly lower than those in the control group (P<0.05). After treatment, PCT and WBC levels in both groups were significantly lower than those before treatment (P<0.05). The levels of PCT and WBC in the observation group were significantly lower than those in the control group (P<0.05). The extubation time, extubation success rate and antibiotic use time in the observation group were significantly shorter than those in the control group (P<0.05). Conclusion Airway clearance technique combined with Tanreqing injection is effective in the treatment of patients with stroke associated pneumonia after tracheotomy. It can effectively improve their neurological function, control lung infection, reduce the level of serum inflammatory factors, shorten the time of extubation, and improve the success rate of extubation.

Key words: stroke, pneumonia, tracheotomy, airway clearance technique, tanreqing injection

中图分类号:

R743.3

罗辉, 吴颖, 仝霖, 谭华桥, 陈成. 气道廓清技术联合痰热清注射液对脑卒中相关性肺炎气管切开患者的影响[J]. 中华养生保健, 2022, 40(23): 161-164.

LUO Hui, WU Ying, TONG Lin, TAN Hua-qiao, CHEN Cheng. Effect of Airway Clearance Technique combined with Tanreqing Injection on Patients with Stroke associated Pneumonia undergoing Tracheotomy[J]. ZHONGHUA YANGSHENG BAOJIAN, 2022, 40(23): 161-164.

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