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中华养生保健 ›› 2022, Vol. 40 ›› Issue (18): 8-11.

• 论著 • 上一篇    下一篇

高压氧联合药物治疗脑神经损伤早期的效果评价

付微, 刘飞, 黄蕊, 张绪东, 梁军, 闫磊, 张平*   

  1. 牡丹江医学院基础医学院,黑龙江 牡丹江,157011
  • 出版日期:2022-09-16 发布日期:2022-09-13
  • 通讯作者: * 张平,E-mail:913689631@qq.com。
  • 作者简介:付微(1991.7-),女,汉族,籍贯:山东省青岛市,硕士研究生,研究实习员,研究方向:基础医学。
  • 基金资助:
    黑龙江省省属本科高校基本科研业务费项目(2019- KYYWF-0939)

Evaluation of Hyperbaric Oxygen Combined with Drugs in the Treatment of Early Brain Nerve Injury

FU Wei, LIU Fei, HUANG Rui, ZHANG Xu-dong, LIANG Jun, YAN Lei, ZHANG Ping*   

  1. Department of Basic Medicine, Mudanjiang Medical College, Mudanjiang Heilongjiang, 157011, China
  • Online:2022-09-16 Published:2022-09-13

摘要: 目的 分析脑神经损伤早期利用高压氧联合药物治疗的临床效果。方法 选取牡丹江医学院附属红旗医院2019年2月~2021年1月收治的50例脑神经损伤患者作为研究对象,将其用随机数表法分成探究组和一般组,每组25例。探究组均采用高压氧联合硝酸甘油、阿司匹林肠溶片治疗,一般组患者应用硝酸甘油、阿司匹林肠溶片治疗。对比两组患者治疗前后神经功能缺损评分、运动功能评分、吞咽功能评分、生活能力评分、神经功能改善时间、运动功能改善时间、吞咽功能改善时间、住院时间,计算并比较治疗有效率、不良反应发生率。结果 治疗后,探究组神经功能缺损评分对比一般组更低,运动功能评分、吞咽功能评分、生活能力评分对比一般组更高,差异有统计学意义(P<0.05);运动功能改善时间、吞咽功能改善时间、住院时间对比结果显示,探究组相比一般组更短,差异有统计学意义(P<0.05);探究组治疗有效率与一般组对比更高,不良反应发生率与一般组对比更低,差异有统计学意义(P<0.05)。结论 应用高压氧联合药物治疗脑神经损伤患者,可缩短其症状消失时间,改善患者神经功能缺损,提高患者运动功能、吞咽功能及生活能力。

关键词: 高压氧, 药物, 脑神经损伤, 治疗有效率

Abstract: Objective To analyze the clinical effect of hyperbaric oxygen combined with pharmacotherapy in the early stage of cerebral nerve injury. Methods Fifty patients with brain nerve injury treated in the Hongqi Hospital Affiliated to Mudanjiang Medical College from February 2019 to January 2021 were selected as the research objects. They were randomly divided into the exploration group and the general group, with 25 cases in each group. The study group was treated with hyperbaric oxygen combined with nitroglycerin and aspirin enteric coated tablets, while the general group was treated with nitroglycerin and aspirin enteric coated tablets. The neurological deficit score, motor function score, swallowing function score, life ability score, neurological function improvement time, motor function improvement time, swallowing function improvement time and hospitalization time of the two groups were compared before and after treatment, and the treatment efficiency and the incidence of adverse reactions were calculated and compared. Results After treatment, compared to control group, the neural deficiency score of the investigation group was lower, whereas the movement function score, swallowing function score and living ability score were higher, which was significant in statistics(P<0.05). By comparison with control group, the improvement time of movement function, improvement time of swallowing function and hospital stay in investigation group were significantly much shorter, which was significant in statistics(P<0.05). The response rate of investigation group was higher than that of control group, while the incidence of side effects was lower, which was significant in statistics(P < 0.05). Conclusion The application of hyperbaric oxygen combined with pharmacotherapy in the treatment of cerebral nerve injury could shorten the time of symptoms, improve the deficiency of neural function, and enhance the movement function, swallowing function and living ability of patients.

Key words: hyperbaric oxygen, drugs, cerebral nerve injury, response rate

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