鼻中隔偏曲矫正术对阻塞性睡眠呼吸暂停低通气综合征合并心衰患者的疗效研究

摘要/Abstract

摘要： 目的研究鼻中隔偏曲矫正术对阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypopnea syndrome,OSAHS）合并心衰患者的疗效。方法选取甘肃省武威市人民医院2015年6月~2019年6月收治的100例OSAHS合并心衰患者作为研究对象,按照随机数表法分为传统组和矫正组,各50例。传统组给予基于持续气道正压通气（CPAP）的常规治疗,矫正组在传统组治疗的基础上给予鼻中隔偏曲矫正术治疗,比较两组患者鼻腔容积水平、肺功能指标一秒用力呼气容积（FEV₁）与FEV/用力肺活量（FVC）、颈股脉搏波传导速度（cfPWV）、左室射血分数（LVEF）及血压。结果治疗后,矫正组与传统组患者鼻腔容积均明显高于治疗前,差异有统计学意义（P<0.05）;矫正组患者鼻腔容积明显高于传统组,差异有统计学意义（P<0.05）;治疗后,矫正组与传统组患者FEV₁与FEV/FVC等肺功能指标均明显高于治疗前,差异有统计学意义（P<0.05）;矫正组患者FEV₁与FEV/FVC等肺功能指标均明显高于传统组,差异有统计学意义（P<0.05）;治疗后,矫正组与传统组患者LVEF明显高于治疗前,且矫正组高于传统组,差异有统计学意义（P<0.05）;治疗后,矫正组与传统组患者颈股脉搏波传导速度（cfPWV）明显低于治疗前,且矫正组低于传统组,差异有统计学意义（P<0.05）。矫正组与传统组治疗后2周的动态收缩压与动态舒张压明显低于治疗前,矫正组也明显低于传统组,差异有统计学意义（P<0.05）。结论鼻中隔偏曲矫正术治疗OSAHS合并心衰,能显著提高患者的鼻腔容积,改善肺功能,还可持续降低患者的动态血压,改善患者的心功能,值得临床应用。

关键词: 阻塞性睡眠呼吸暂停低通气综合征, 鼻中隔偏曲矫正术, 鼻腔容积

Abstract: Objective To explore and analyze the effect of nasal septum deviation correction on obstructive sleep apnea hypopnea syndrome patients with heart failure. Methods A total of 100 patients with OSAHS complicated with heart failure admitted to Wuwei People’s Hospital of Gansu Province from June 2015 to June 2019 were selected as the research subjects, and they were divided into the traditional group and the corrected group according to the random number table method, with 50 patients in each group. The traditional group was treated with conventional treatment based on Continuous positive airway pressure (CPAP), and the correction group was treated with nasal septum deviation correction on the basis of the traditional treatment. The level of nasal volume, lung function index forced expiratory volume in one second (FEV₁), FEV/forced vital capacity (FVC), and Cervical pulse wave velocity were compared between the two groups. CfPWV, Left ventricular ejection fraction (LVEF) and blood pressure. Results After treatment, the nasal volume of the corrected group and the traditional group was significantly higher than before, with statistical significance (P<0.05). The nasal volume in the corrected group was significantly higher than that in the traditional group, with statistical significance (P<0.05). After treatment, FEV₁, FEV/FVC and other lung function indexes in the correction group and the traditional group were significantly higher than before treatment, with statistical significance (P<0.05). FEV₁, FEV/FVC and other lung function indexes in the corrected group were significantly higher than those in the traditional group, with statistical significance (P<0.05). After treatment, LVEF in the correction group and the traditional group was significantly higher than before treatment, the difference was statistically significant (P<0.05). After treatment, CfPWV in the corrected group and the traditional group was significantly lower than before treatment, the difference was statistically significant (P<0.05), and there was also a significant difference between the corrected group and the traditional group (P<0.05). The dynamic systolic blood pressure and dynamic diastolic blood pressure at 2 weeks after treatment in the correction group and the traditional group were significantly lower than before treatment (P<0.05), and the correction group was also significantly lower than the traditional group (P<0.05). Conclusion Correction of nasal septum deviation in the treatment of OSAHS complicated with heart failure can significantly improve the nasal volume of patients, improve lung function, promote the continuous reduction of ambulature blood pressure and improve the heart function of patients, which is worthy of clinical application.

Key words: Nasal septum deviated correction, obstructive sleep apnea hypopnea syndrome, nasal volume

中图分类号:

R766

董跃峰. 鼻中隔偏曲矫正术对阻塞性睡眠呼吸暂停低通气综合征合并心衰患者的疗效研究[J]. 中华养生保健, 2022, 40(16): 8-11.

DONG Yue-feng. Study on the Efficacy of Septum Deviation Correction in Patients with Obstructive Sleep Apnea-hypopnea Dyndromeand Heart Failure[J]. ZHONGHUA YANGSHENG BAOJIAN, 2022, 40(16): 8-11.

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