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中华养生保健 ›› 2025, Vol. 43 ›› Issue (11): 31-35.

• 中医诊疗 • 上一篇    下一篇

基于数据挖掘的中成药治疗心悸用药规律研究

周千, 叶孝红*   

  1. 昆山市第五人民医院药剂科,江苏 苏州,215300
  • 出版日期:2025-06-01 发布日期:2025-09-23
  • 通讯作者: *叶孝红,E-mail:214273716@qq.com。
  • 作者简介:周千(1989—),女,汉族,籍贯:江苏省苏州市,本科,主管中药师,研究方向:医院药事管理。

A Study on the Regularity of Traditional Chinese Patent Medicines and Simple Preparations in the Treatment of Palpitations Based on Data Mining

ZHOU Qian, YE Xiao-hong*   

  1. Department of Pharmacy, Kunshan Fifth People's Hospital, Suzhou Jiangsu, 215300, China
  • Online:2025-06-01 Published:2025-09-23

摘要: 目的 讨论中成药治疗心悸的用药规律,为临床应用提供用药参考。方法 收集《中药成方制剂》治疗心悸的中成药处方,将药物录入中医传承计算平台(V3.5),对药物进行数据分析。结果 中成药治疗心悸处方182首。从性味来看,使用频次最高的是温性药物、甘味药物,其次是平性药物、苦味药物;从归经来看,使用频次最高的是归心经药物,其次是归肾经药物,再次是归肝经药物;从用药频次来看,使用频次前10位的中药分别是当归、五味子、人参、茯苓、黄芪、甘草、麦冬、远志、党参、熟地黄;从功效来看,使用频次最多的是补虚类中药,其次是安神类中药,再次是活血化瘀类中药;从药物组合来看,常以五味子配伍麦冬,当归配伍茯苓、黄芪、甘草使用;设置支持度≥15%,置信度≥0.7,得到由“黄芪、茯苓、当归、酸枣仁、甘草、熟地黄、远志、五味子、麦冬、人参”组成的药物规律网络化展示图;得到新方3首。结论 心悸的病因与情志、饮食、久病体虚有关,基本病机为心脉阻滞,心神失养。中成药治疗心悸重视心、肾、肝、肺、脾五脏,虚证补益人体气血阴阳为主,实证以祛除人体有形实邪为主,以生脉饮、归脾汤、炙甘草汤为基础方加减使用。

关键词: 中成药, 《中药成方制剂》, 心悸, 用药规律, 数据挖掘

Abstract: Objective To discuss the medication rule of traditional Chinese patent medicines and simple preparations in the treatment of palpitation, and provide a reference for clinical application. Methods Collect the prescriptions of traditional Chinese patent medicines and simple preparations for the treatment of palpitations in Formulated Preparations of Traditional Chinese Medicine, input the drugs into the traditional Chinese medicine inheritance calculation platform (V3.5), and analyze the data of the drugs. Results There were 182 prescriptions of traditional Chinese patent medicines and simple preparations for palpitation.From the perspective of taste, the most frequently used are warm and sweet drugs, followed by mild and bitter drugs;From the perspective of meridian regulation, the most frequently used drugs are those for the heart meridian, followed by those for the kidney meridian, and then those for the liver meridian;In terms of medication frequency, the top 10 traditional Chinese medicines are Angelica sinensis, Schisandra chinensis, ginseng, Poria cocos, Astragalus membranaceus, licorice, Ophiopogon japonicus, Radix Codonopsis pilosula, and Radix Rehmanniae;In terms of efficacy, the most frequently used traditional Chinese medicines are those that tonify deficiency, followed by those that calm the nerves, and then those that promote blood circulation and remove blood stasis;From the perspective of drug combinations, Schisandra chinensis is often used in combination with Ophiopogon japonicus, while Angelica sinensis is used in combination with Poria cocos, Astragalus membranaceus, and licorice;Set the support level to≥15% and confidence level to≥0.7, and obtain a networked display of drug patterns consisting of "Huangqi, Fuling, Danggui, Suanzaoren, Licorice, Rehmannia glutinosa, Yuanzhi, Schisandra chinensis, Ophiopogon japonicus, and Ginseng";Obtain three new songs. Conclusion The etiology of palpitations is related to emotions, diet, and long-term physical weakness. The basic pathological mechanism is heart block and loss of mental and spiritual nourishment.Traditional Chinese patent medicines and simple preparations focuses on the heart, kidney, liver, lung and spleen in the treatment of heart palpitations. Deficiency syndrome is mainly used to supplement the qi, blood, yin and yang of the human body. The excess syndrome is mainly used to eliminate the visible and real evils of the human body. It is added or subtracted based on Shengmai Decoction, Guipi Decoction and Zhigancao Decoction.

Key words: traditional Chinese patent medicines and simple preparations, Traditional Chinese Medicine Formula Preparation, Palpitations, Medication rules, data mining

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