菊苣竹叶提取物对良性前列腺增生患者术后排尿功能的影响

中华养生保健 ›› 2025, Vol. 43 ›› Issue (11): 6-8.

菊苣竹叶提取物对良性前列腺增生患者术后排尿功能的影响

陈勇¹, 李江¹, 隆毅², 李建升⁴, 姜川⁴, 郭林⁴, 迟春华⁴, 管庆磊^3,*

1.济南市中西医结合医院泌尿外科,山东济南,271100;
2.山东中医药大学第二附属医院药学部,山东济南,250000;
3.知岐健康产业（山东）集团有限公司研发部,山东济南,250000;
4.山东中医药大学附属医院肛肠科,山东济南,250014

出版日期:2025-06-01 发布日期:2025-09-23
通讯作者: ^*管庆磊,E-mail：fsjhla@sina.com。
作者简介:陈勇（1981—）,男,汉族,籍贯：山东省济南市,本科,主治医师,研究方向：中医外科学。
基金资助:
山东省中医药科技项目（M-2023169）; 山东省科技型中小企业创新能力提升工程（2022TSGC2125）

Influence of Cichorium Intybus and Bamboo Leaf Extract on Postoperative Urinary Function in Patients with Benign Prostatic Hyperplasia

CHEN Yong¹, LI Jiang¹, LONG Yi², LI Jian-sheng⁴, JIANG Chuan⁴, GUO Lin⁴, CHI Chun-hua⁴, GUAN Qing-lei^3,*

1. Department of Urology, Jinan Hospital of Integrated Traditional Chinese and Western Medicine, Jinan Shandong, 271100, China;
2. Department of Pharmacy, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan Shandong, 250000, China;
3. Department of Research and Development, Zhiqi Health Industry (Shandong) Group Co., Ltd., Jinan Shandong, 250000, China;
4. Department of Proctology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan Shandong, 250014, China

Online:2025-06-01 Published:2025-09-23

摘要/Abstract

摘要： 目的探讨菊苣竹叶提取物对良性前列腺增生患者术后排尿功能恢复的价值。方法选取2023年9月—2024年8月济南市中西医结合医院收治的120例良性前列腺增生患者作为研究对象,随机分为对照组和试验组,每组60例。对照组仅接受常规术后盆底肌功能训练,试验组在常规术后护理基础上加用菊苣竹叶提取物治疗。对比两组疗效、国际前列腺症状评分（IPSS）、中医证候积分、排尿功能指标及炎症因子水平。结果试验组总有效率显著高于对照组,差异有统计学意义（P<0.05）。治疗4周后,与对照组比较,试验组的IPSS评分、中医证候积分、最大尿流速、平均尿流速均更高,同时,试验组的干扰素γ（IFN-γ）、肿瘤坏死因子α（TNF-α）均高于对照组,差异有统计学意义（P<0.05）。结论菊苣竹叶提取物对良性前列腺增生患者术后排尿功能具有改善作用。

关键词: 菊苣竹叶提取物, 良性前列腺增生, 术后排尿功能, 随机对照试验

Abstract: Objective The aim of this study was to investigate the potential benefits of chicory and bamboo leaf extract in facilitating the recovery of urinary function following surgery for patients with benign prostatic hyperplasia (BPH). Methods A total of 120 patients diagnosed with BPH and admitted to Jinan Hospital of Integrated Traditional and Western Medicine between September 2023 and August 2024 were enrolled in this study. The patients were randomly assigned to either a control group or an experimental group, with 60 patients in each group. The control group received only standard postoperative care, whereas the experimental group received standard postoperative care plus additional treatment with chicory and bamboo leaf extract. The efficacy of the treatment, assessed through the International Prostate Symptom Score (IPSS), Traditional Chinese Medicine (TCM) syndrome score, urinary function indicators, and levels of inflammatory factors, was compared between the two groups. Results The overall effective rate in the experimental group was significantly higher than that in the control group. After four weeks of treatment, the experimental group showed higher scores on the IPSS, TCM syndrome score, maximum urinary flow rate, and average urinary flow rate compared to the control group. Furthermore, the levels of IFN-γ and TNF-α in the experimental group were also higher than those in the control group, with statistically significant differences observed (P<0.05). Conclusion The findings of this study suggest that chicory and bamboo leaf extract has a positive effect on improving urinary function recovery after surgery for patients with BPH. The higher efficacy rate and improved urinary function indicators in the experimental group indicate that the addition of chicory and bamboo leaf extract to standard postoperative care may provide an effective therapeutic approach for enhancing postsurgical recovery in BPH patients. Further research is needed to elucidate the mechanisms underlying these effects and to confirm the long-term benefits of this treatment. This study highlights the potential of natural extracts in complementing conventional medical treatments and offers promising avenues for future research in the field of urology and integrative medicine.

Key words: Cichorium intybus and bamboo leaf extract, benign prostatic hyperplasia, postoperative urinary function, randomized controlled trial

中图分类号:

R699.8

陈勇, 李江, 隆毅, 李建升, 姜川, 郭林, 迟春华, 管庆磊. 菊苣竹叶提取物对良性前列腺增生患者术后排尿功能的影响[J]. 中华养生保健, 2025, 43(11): 6-8.

CHEN Yong, LI Jiang, LONG Yi, LI Jian-sheng, JIANG Chuan, GUO Lin, CHI Chun-hua, GUAN Qing-lei. Influence of Cichorium Intybus and Bamboo Leaf Extract on Postoperative Urinary Function in Patients with Benign Prostatic Hyperplasia[J]. ZHONGHUA YANGSHENG BAOJIAN, 2025, 43(11): 6-8.

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